Hands-on NMR-based Metabolomics: principles, methods and applications

Unidade de investigação   22 de maio de 2022
Ficheiro com o nome: BANNER_FCS311

Course format: hybrid (online theoretical lectures; on-site hands-on sessions)

6th to 9th June, 2022

[poster] [programme] [registration]

Venue (hands-on sessions): NMR facility, Health Sciences Research Centre (CICS-UBI), Faculty of Health Sciences, University of Beira Interior, Covilhã, Portugal

Course overview:
Metabolomics is an emerging field that aims to investigate changes in the synthesis and consumption of small molecules – metabolites – in biological systems. These small molecules may be substrates, intermediary metabolites and the end-products of metabolism. Thus, the analysis of metabolome provides a comprehensive picture of body function and valuable information for understanding disease mechanisms as well as help in disease management, diagnosis and prognosis. Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful techniques used for metabolomic analyses, due to its high reproducibility and quantitative accuracy, as well as minimal sample preparation.
This course provides an introduction to NMR-based metabolomics, describing the methods used to study the metabolome, from sample preparation to the analysis of NMR spectra and metabolomics data.
The course comprises theoretical lectures (online) and hands-on practical sessions (on-site, at the NMR facility of CICS-UBI), where participants will be able to perform NMR-based metabolomics experiments in the laboratory and have an overview on statistical methods and some specific software platforms that can used for metabolomics data analysis.

Target audience:
This course is aimed at MSc, PhD students and researcher scientists who are interested in the metabolomics field using NMR spectroscopy.

Participants:
Limited to 17 participants – for attending the complete course (theoretical + hands-on sessions)
Unlimited number of participants – for attending theoretical lectures (online), only

Language:
The course will be taught in English.

Course topics:
- Introduction to metabolomics: methods and applications
- Metabolomics NMR procedures, including sample preparation methods and NMR spectra acquisition
- Univariate and multivariate statistical analysis of NMR data

Course instructors:
Oscar Millet (CIC bioGUNE, Spain) – theoretical lectures (online)
Roland Leiminger (Bruker BioSpin, Germany) – theoretical lectures (online)
Claire Clannet (Bruker BioSpin, Germany) – Hands-on (on-site)
Luís Gafeira (ITQB-Nova, Portugal) – Hands-on (on-site)
Carla Cruz (CICS-UBI) – Hands-on (on-site)
Carla Fonseca (CICS-UBI) – Hands-on (on-site)

Important deadlines:
- May 31th, 2022 - Registration deadline for the complete course (theoretical lectures + hands-on sessions)
- June 3rd, 2022 - Registration deadline for theoretical lectures, only

Registration:
For registration, applicants should fill in the following application form (until May 31th for complete course participation; until June 3rd for participation in theoretical lectures, only).
Registration will only be validated after submitting the registration form and sending the bank transfer confirmation by e-mail to course coordination (rmn.cicsubi2022@gmail.com).

IMPORTANT NOTE: After registration, and before proceeding with the bank transfer, please wait for the confirmation sent by the course coordination to the applicant's e-mail.

Registration Fees:
Theoretical lectures (only) - 15€ (includes access to theoretical course materials and participation certificate)
Complete course (theoretical lectures + hands-on sessions) - 150€ (includes access to all course materials, coffee breaks and participation certificate)

Course payment:
Registration fees should be paid through bank transfer to the following account number:
IBAN: PT50 0018 0003 2727 2335 0205 1 ; BIC/Swift: TOTAPTPL

Course Organizers:
Carla Cruz (CICS-UBI)
Carla Fonseca (CICS-UBI)
Sandra Bernardo (CICS-UBI)
Tiago Santos (CICS-UBI)
Contact: rmn.cicsubi2022@gmail.com

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