| Code |
11840
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| Year |
1
|
| Semester |
S1
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| ECTS Credits |
6
|
| Workload |
PL(15H)/T(30H)/TP(15H)
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| Scientific area |
Biochemistry
|
|
Entry requirements |
No requirements.
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|
Mode of delivery |
Teorical classes by the implementation of a tutorial system and pratical classes in a typical laboratory format.
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|
Work placements |
Not applicable.
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Learning outcomes |
To Understand the function of cell organelles.
To Acquire knowledge about chemical composition, structural and biomolecules properties.
To Integrate processes and life mechanisms: molecular and cell levels.
To Acquire pratical manipulation at biological laboratory techniques.
To Acquire teorical and practical knowledge about cellular biology and cellular structure.
To Understand basic life cellular mechanisms.
To Understand and integrate the molecular, structural, cellular and physiological basis of organelles.
To Understand the relevance of cellular signalization on communication and cell life.
To Differentiate signalization molecules, cell receptors and signalization types.
To Integrate signalization mechanisms on physiological regulation.
To Describe mitotic, meiotic and apoptotic mechanisms.
To Distinguish by optic microscopic cells on mitotic and meiotic states.
To Discriminate the major diferences between apoptotic and necrotic cells.
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Syllabus |
Prokaryotic and eucariotic cells. Endosymbiotic theory. Cytoskeleton, chromosomes, nuclear envelope and
nucleus (elementary notions of gene expression). Dynamics and regulation, nuclear transport, aggregation and
disaggregation. Compartmentation, structure and function of the cytoplasmic membrane, hialoplasma,
cytoskeleton, microfilaments, intermediate filaments, microtubules. Mitochondria, chloroplasts, ribosomes,
endoplasmic reticulum, Golgi complex: morphology, composition and functions .Lysosomes and peroxisome:
structure and functions. Signalization: paracrine, endocrine, autocrine and synaptic. Membrane receptors
coupled to G protein and ion channels, tyrosine kinase and phosphatase. Nitric oxide, acetylcholine, and
phospholipase C signalization via. CAMP and Ca+2. Mitosis and Meiosis: phases and checkpoints. Apoptosis
and effectors. P: Quantification of proteins, amino acids, vitamin C and amido assessement, microscopy, and
mitotic phases.
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Main Bibliography |
- Biologia Celular e Molecular, Carlos Azevedo, 4ª edição, Lidel, edições técnicas, Lisboa, 2005.
- Molecular Cell Biology, Lodish et al., 5th edition, W. H. Freeman and Company, 2004.
- Molecular Biology of the Cell, Alberts et al, 3th or 4th Edition, Garland Publishing.
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Language |
Portuguese. Tutorial support is available in English.
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