Bioprocesses

Code	11855
Year	2
Semester	S2
ECTS Credits	6
Workload	TP(60H)
Scientific area	Biotecnologia
Entry requirements	-
Mode of delivery	Face-to-face with recourse to e-learning.
Work placements	Not applicable
Learning outcomes	Establish mass and energy balances in processes with and without chemical reaction. Solve combined mass and energy balances in transient regime. Know momentum, heat and mass transport phenomena. Perform calculations of heat and mass transfer in bioprocesses. At the end of this curricular unit, the student should be able to: - Design and interpret a flow diagram of an industrial chemical process; - Perform mass balances in systems with chemical reaction; - Perform energy balances in processes with phase transition and chemical reaction; - Carry out combined mass and energy balances with phase transition and chemical reaction, in steady state or batch systems. - Set up material and energy balances and identify knowns and unknowns in bioprocesses
Syllabus	Introduction to mass balances. Systems and processes. Flowsheet. Equilibrium and steady state. Mass balances with recycling, purge and bypass. Stoichiometry of growth and product formation. Balance to the atoms. Balance to the electrons. Yield. Energy balances. Enthalpy changes in processes with and without chemical reaction. Heat of reaction in processes with biomass production. Energy balances in microbial cultures. Energy balances in fermentation processes. Introduction to mass and energy balances in unsteady state.
Main Bibliography	- Lopes, A. M. C.; Nunes, M. J. "Apontamentos para a cadeira de Processos Químicos", UBI, Covilhã, 2002. - Hougen, O. A.; Watson, K. M.; Ragatz, R. A. "Princípios dos Processos Químicos", Ed. Lopes da Silva, 1972. - Himmelblau, D. M. "Basic Principles and Calculations in Chemical Engineering", 6th Ed., Prentice-Hall, New Jersey, 1996. - Lemos, F.; Madeira Lopes, J.; Ramôa Ribeiro, F. "Reactores Químicos", IST Press, 2002. - Nunes dos Santos, A.M. "Reactores Químicos", vol. I, Fundação Calouste Gulbenkian ed., 1990. - Baley, J.E.; Ollis, D.F. "Biochemical Engineering Fundamentals ", 2nd Ed., McGraw-Hill, 1986. - Nielsen, J.; Villadsen, J.; Lidén, G. "Bioreaction Engineering Principles", 2nd Ed., Kluwer Academic/ Plenum Plublishers, New York, 2003. - "Perry’s Chemical Engineer’s Handbook", 7th Ed., Perry, R.H., Green, D.W.; Maloney, J.O. (Eds) McGraw-Hill, New York, 1999.
Language	Portuguese. Tutorial support is available in English.