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Biosystems Control

Biosystems Control

Code	13415
Year	3
Semester	S1
ECTS Credits	6
Workload	PL(30H)/T(30H)
Scientific area	Biomedical Sciences
Entry requirements	Not applicable.
Mode of delivery	Face-to-face
Work placements	--
Learning outcomes	The purpose of this course is to provide students of the first cycle in Biomedical Sciences the fundamental concepts of physiological control systems present in the human body. Be able to discuss the differences between technological and physiological control systems. Be able to analyze systems according to their properties and to understand the utility of employing time-domain descriptions of linear systems. Understand and be able to apply the techniques for steady-state analysis of physiological closed-loop systems. Be able to perform the transient response analyses of closed-loop systems and discuss the effect on system dynamics of “closing the loop”, as well as changing the type of feedback. Understand and be able to apply a range of techniques for assessing stability under conditions in which the assumption of linearity can be made.
Syllabus	1. Introduction 1.1 Systems analysis: fundamentals concepts 1.2 Differences between engineering and physiological control systems 2. Mathematical modeling 2.1 Generalized systems properties 2.2 Models with combinations of system elements 2.3 Superposition principle 2.4 Models of physiological systems 2.5 The time response and linear convolution 2.6 State-space analysis 2.7 Computer analysis and simulation 3. Static analysis 3.1 Introduction 3.2 Open and close -loop systems 3.3 Steady-state operating point 3.4 Steady-state analysis 3.5 Application Problems in Biosystems 4. Time-domain analysis 4.1 system response: open-loop versus closed-loop 4.2 Transient response analysis 4.3 Step response 5. Stability analysis 5.1 Stability and transient response 5.2 Root locus 5.3 Stability analysis of the pupillary light reflex
Main Bibliography	[1] KHOO, Michael CK. Physiological control systems: analysis, simulation, and estimation. John Wiley & Sons, 2018. [2] Ogata, K. Modern control engineering (Vol. 5). Upper Saddle River, NJ: Prentice hall, 2010. [3] Dorf, Richard C. , Bishop, Robert H. – Modern Control Systems – 12th Edition, Pearson, 2010. [4] Chappell, M., and S. J. Payne. Physiology for Engineers. New York: Springer, 2020. [5] NISE, Norman S. Control systems engineering. John Wiley & Sons, 2020.
Teaching Methodologies and Assessment Criteria	The evaluation is continuous according to the model: solving exercises and simulation problems (Matlab / Simulink) (30%), two written test (35%+35%). Failure in this model implies examination evaluation. Students must attend at least 80% of contact hours.
Language	Portuguese. Tutorial support is available in English.