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Human Pathophysiology and Pharmacology

Code 13656
Year 3
Semester A1
ECTS Credits 20
Workload PL(60H)/TP(200H)
Scientific area Ciências Farmacêuticas
Entry requirements N.A.
Mode of delivery The sessions are daytime and attending with small groups of students. The topics are organized in Pedagogic Units (PU) with continuous evaluation along the year.
Work placements Not applicable.
Learning outcomes 1) To explain the diseases pathophysiology
2) To understand the drug actions as modifiers of the pathophysiology mechanisms of the diseases and the drugs structure-activity relationship.
3) To recognize the link between the disease pathophysiology and the clinical biochemical parameters
Syllabus PU1: Basic pathophysiology. Basic Pharmacodynamics and Pharmacokinetics. Basic principles of biochemical clinic analysis.
PU2: Mechanism participating and drugs used in inflammation, fever e pain. Anaesthetic drugs. Drugs used in transplant and autoimmune diseases.
PU3: Drugs acting in the peripheral nervous system. Neuromuscular diseases. Spasmolytic.
PU4: Central nervous system diseases and used drugs.
PU5: Drugs used to treat cardiovascular and renal diseases. Analytics used to make diagnosis of these diseases.
PU6: Drugs used to treat respiratory and digestive diseases. Analytics used to make diagnosis of these diseases.
PU7: Drugs used to treat metabolic and endocrinology system pathologies. Analytics used to make diagnosis of these diseases.
PU8: Drugs used to treat pathologies related with neoplastic growth, blood or immune system. Analytics used to make diagnosis of these diseases.
Main Bibliography ABBAS A (2015). Cellular and Molecular Immunology. AKDIS CA (2014). Global Atlas of Allergy. ARNESON W (2007). Clinical chemistry. A laboratory perspective. BATTISTA E (2015). Crash course: Pharmacology. BURTIS CA (2014) Tietz Fundamentals of Clinical Chemistry. CASTRO S (2013). Manual de Patologia General. COHEN BJ (2005). Memmler's the human body in health and disease. DIPIRO JT (2020). Pharmacotherapy: A Pathophysiologic Approach. GOODMAN & GILMAN'S (2017). The Pharmacological Basis of Therapeutics. GROSSNAN SC (2014). Porth pathophysiology. HUETHER S (2017) Study Guide for Understanding Pathophysiology. LEMKE (2012). Foye’s Principles of Medicinal Chemistry. McPHERSON RA (2017). Henry’s clinical diagnosis and management by laboratory methods. RANG HP (2015). Pharmacology. RITTER (2008). A textbook of clinical pharmacology and therapeutics. WHALEN K (2018) Pharmacology.
Teaching Methodologies and Assessment Criteria a) Pedagogic methodology centered in the student. The participation of the student in the learning process allows a higher development of his reasoning capabilities, self-learning and self-evaluation.
b) Learning involving the integration of different basic scientific areas and also clinical areas related with pathology.
c) Organization of the learning topics by pedagogic Unites (PU) and performing of continuous evaluation along the year.
d) Learning activities in small groups of students and using convenient resources to achieve self-learning and to have a personalized follow-up along all the process.

Language Portuguese. Tutorial support is available in English.
Last updated on: 2023-10-02

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