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Clinical Chemical Biological Analysis Course

Code 13694
Year 4
Semester S2
ECTS Credits 3
Workload TP(30H)
Scientific area Physics and Chemistry
Entry requirements Not applicable
Learning outcomes Prepare the 1st contact with a Laboratory of Clinical Analysis. Theoretical-practical bases in the area of ??Clinical Analysis. Acquire clinical-laboratory knowledge for integration into specific / multidisciplinary teams. Consolidate essential knowledge to the pharmacist, whatever the area, constituting extension to areas of specialization. Know the hierarchy. Basis of quality criteria in the clinical laboratory, as well as acquiring Quality Management capabilities for systems certification and trial accreditation. To know how to apply knowledge and to interconnect the different laboratory values ??in the understanding and interpretation of results in situations of disease / action of drugs. Know different methodologies of different complexity. Know how to process biological samples, interpret an analytical request, frame alterations of bulletins in different pathologies and interconnect mechanisms underlying the pathological situation. Know how to identify emergency pictures.
Syllabus -The Laboratory of Clinical Analysis and its evolution in the concept, dynamic, in the knowledge of new methodologies used
- Basic concepts of hematology
- Pathologies of the Erythrocytes
- Pathologies of the Linfocytes
- Hemostasis: most commonly used tests
- Change in metabolism of carbohydrates and lipids
- Impaired hepatic and renal function
- Special biological fluids
Parameters of greater laboratory importance (proteins, enzymes and tumor markers).
- Diagnosis and follow-up of the main maternal-fetal infections: Clinical signs, complications and evolution for chronicity. Particular reference to the laboratory profile of hepatitis A, B and C.
- Serological diagnosis of some infectious diseases.
- Importance of bacteriological exams of different fluids: urine, expectoration, SCF, feces, genital exudates, nasopharyngeal exudates, pus of wounds. Bacterial prevalence in different products. The importance of the antibiogram.
- Quality in LAC
Main Bibliography Henry's Clinical Diagnosis and Management by Laboratory Methods, 22nd Edition (2012), McPherson R.A., Pincus M.R., Sanders Elsevier.
- Essencial Haematology, 8thEdition (2016), Hoffbrand A.V. and Pettit J.E. by Blackwell Scientific Publications.
- Basic & Clinical Endocrinology (Langue Medical Books), David Gardner, Dolores Shoback, 10thEdition (2017)
- Fauci AS, Brawnwald E, Issebacher KJ, Martin JB, Kasper DL, Hauser SL, Longo DL, editors. Harrison’s Principles of Internal Medicine. 15ª Edição, New York, MacGraw-Hill, 2002
- Westgard, JO; Barry, PL; Hunt, MR; Groth, T., A multi-rule Shewhart chart for quality control in clinical chemistry. Clin Chem 1981; 27:493-501
- Westgard, JO. Power functions for Statistical Control Rule. Clin Chem 1979, 25: 863-869
- Standard NP EN ISO 15189: 2007
Language Portuguese. Tutorial support is available in English.
Last updated on: 2022-06-20

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