| Code |
15120
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| Year |
2
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| Semester |
A1
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| ECTS Credits |
7
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| Workload |
OT(64H)/PL(6H)/S(2H)/TP(8H)
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| Scientific area |
Morphological and Functional Sciences
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Entry requirements |
Not applicable
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Learning outcomes |
Provide students with in-depth knowledge of the endocrine and metabolic system through an integrated approach to the anatomy, physiology, histology, embryology and biochemistry of this system.
At the end of the course unit the learner is expected to be able to
- integrate the knowledge of endocrinology with those acquired in previous periods of their training, cellular and molecular mechanisms;
- describe the microscopic and macroscopic morphology of the endocrine system and its embryonic development;
- characterize the endocrine system relating the chemical structure of hormones with the functions they perform.
- interpret the action of hormones in the regulation of carbohydrates, lipids and nitrogen compounds metabolism and calcium and phosphorus homeostasis;
- interpret clinical problems related to the endocrine system functioning;
- work in team in the resolution of problems and in the acquisition of knowledge.
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Syllabus |
FUNCTIONAL ORGANIZATION OF THE ENDOCRINE SYSTEM
Types of hormones.
Hypothalamic-pituitary axis.
Macroscopic and microscopic morphology of thyroid and parathyroid glands, adrenals and pancreas and their hormones.
NUTRITION AND METABOLISM. REGULATION OF CARBOHYDRATES METABOLISM.
Hormonal regulation of metabolic rate.
Importance of temperature control and body mass for the human body.
Hormonal regulation of glycolysis, gluconeogenesis and glycogen metabolism.
Control of glycemia and tissues involved.
Physiological relevance of the pentose phosphate pathway.
REGULATION OF LIPID AND NITROGEN METABOLISM. METABOLIC INTEGRATION
Hormonal regulation of lipid transport and storage.
Hormonal regulation of lipid synthesis and degradation, metabolism of ketone bodies, cholesterol metabolism and urea cycle in human protein metabolism.
Operation of the different metabolic pathways in periods after meals and in periods of fasting.
HORMONAL CONTROL OF GROWTH.
HORMONAL REGULATION OF MINERAL METABOLISM.
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Main Bibliography |
BIBLIOGRAFIA PRINCIPAL
• BERNE RM, LEVY MN (2017). Physiology. 7th edition. Philadelphia, Mosby/Elsevier.
• Widmaier, E. P., Raff, H., Strang, K. T., & Vander, A. J. (2019). Vander's human physiology: The mechanisms of body function. 15th Edition. Boston, MA: McGraw-Hill.
• Gardner, D. G., Shoback, D. M. (2018). Greenspan's basic & clinical endocrinology. 10th Edition. New York, McGraw-Hill.
• Rodwell, V. W., Bender, D. A., Botham, K. M., Kennelly, P. J., & Weil, P. A. (2018). Harper's illustrated biochemistry. 31st edition. New York, McGraw-Hill.
BIBLIOGRAFIA COMPLEMENTAR
Antonino Belfioread and Derek LeRoith (2018): Principles of Endocrinology and Hormone Action. Springer International Publishing
Guyton, A. & Hall, J. (2020). Textbook of Medical Physiology. 14th Edition. Philadelphia, Saunders/Elsevier.
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Teaching Methodologies and Assessment Criteria |
The teaching/learning activities are centred in the student and in the group interaction and take place through seminars (S), tutorials (OT) and laboratory practice (PL). This course uses Team-Based Learning (TBL), where the three typical stages are used, (1) individual pre-class preparation, (2) ensure learning and (3) application of the concepts. Furthermore, OT sessions are based on learning objectives, with the tutor facilitating group discussion and student participation in the presentation of content. The PL (anatomy, histology and physiology) aim to facilitate the acquisition of knowledge. In Moodle platform are available documents and videos that facilitate self-learning.
In UC will be assessed knowledge, presentation and discussion skills, using the following instruments: Piecemeal tests, Global Test; Oral presentation and discussion of clinical cases.
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Language |
Portuguese. Tutorial support is available in English.
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