Selected Publications

In 2022, the H&M research group published a total of 28 papers in WoS-indexed international journals, with an average impact factor of 5.293. From these, 46.4% were published in journals within the 1st quartile of JCR journal rankings (3.6% in the top decile).

Five main publications:

1) Lorigo M, Cairrao E. UV-B filter octylmethoxycinnamate-induced vascular endothelial disruption on rat aorta: In silico and in vitro approach. Chemosphere. 2022;307(Pt 2):135807. doi: 10.1016/j.chemosphere.2022.135807 (IF 8.943; Q1 Environmental Sciences)
Description: This study of the endocrine-disruptor OMC demonstrated its effect on vascular endothelial cells and suggests that long-term OMC exposure may increase the risk of cardiovascular diseases.

2) Lopes CA, Prazeres S, Martinez-de-Oliveira J, Limbert E, Lemos MC. Iodine Supplementation in Pregnancy in an Iodine-Deficient Region: A Cross-Sectional Survey. Nutrients. 2022;14(7). doi: 10.3390/nu14071393 (IF 6.706; Q1 Nutrition & Dietetics)
Description: This was a study of the effects of iodine supplementation of pregnant women living in an iodine deficient region. Iodine deficiency during pregnancy is a public health problem due to its potential adverse effects on maternal and child health. Iodine supplementation during pregnancy has been recommended by several scientific societies in Europe and North America. This study demonstrated that these recommendations were insufficient in a Portuguese iodine deficient region and that additional measures are needed.

3) Diniz A, Alves MG, Candeias E, Duarte AI, Moreira PI, Silva BM, Oliveira PF, Rato L. Type 2 Diabetes Induces a Pro-Oxidative Environment in Rat Epididymis by Disrupting SIRT1/PGC-1α/SIRT3 Pathway. Int J Mol Sci. 2022;23(16). doi: 10.3390/ijms23168912 (IF 6.208; Q1 Biochemistry & Molecular Biology)
Description: This study demonstrated the pathways by which type 2 diabetes induces a pro-oxidative environment in the testis, therefore contributing to the understanding of the association between diabetes and impaired male reproductive function.

4) Cardoso HJ, Figueira MI, Carvalho TMA, Serra CDM, Vaz CV, Madureira PA, Socorro S. Androgens and low density lipoprotein-cholesterol interplay in modulating prostate cancer cell fate and metabolism. Pathol Res Pract. 2022;240:154181. doi: 10.1016/j.prp.2022.154181. (IF 3.309; Q2 Pathology)
Description: This study showed that androgens deregulate lipid metabolism and enhance the effects of LDL on the viability, proliferation and migration of prostate cancer cells, thereby supporting the clinical link between obesity and prostate cancer.

5) Gaspar LM, Gonçalves CI, Fonseca F, Carvalho D, Cortez L, Palha A, Barros IF, Nobre E, Duarte JS, Amaral C, Bugalho MJ, Marques O, Pereira BD, Lemos MC. A Common Variant in the CDK8 Gene Is Associated with Sporadic Pituitary Adenomas in the Portuguese Population: A Case-Control Study. Int J Mol Sci. 2022;23(19). doi: 10.3390/ijms231911749 (IF 6.208; Q1 Biochemistry & Molecular Biology)
Description: This study involved a national consortium led by CICS-UBI to determine the genetic susceptibility factors for pituitary adenomas. A total of 570 patients and 546 normal controls were genotyped and this revealed that variants at the CDK8 locus increase the susceptibility to sporadic pituitary adenomas in the Portuguese population.

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CICS-UBI - Centro de Investigação em Ciências da Saúde
[Health Sciences Research Center]
Faculdade de Ciências da Saúde
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