Telma Alexandra Quintela Paixão
Regulation of the circadian clock by sex hormones: impact on neurodegeneration
The main aim of my research is to understand the link between choroid plexus, Alzheimer´s disease, and the circadian clock, and clarify how sex steroid hormones can affect biological rhythms. Ongoing work includes an investigation of: (1) the molecular mechanisms of the mammalian circadian clock, with a special focus on the choroid plexus; (2) the influence of sex differences in the choroid plexus circadian clock; (3) sex steroid hormones regulation of the rhythmic gene expression in the choroid plexus; (4) melatonin synthesis in the choroid plexus.
Research GroupNão está associado a nenhum grupo...