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  4. Immunology


Code 10260
Year 3
Semester S1
ECTS Credits 6
Workload PL(30H)/T(30H)
Scientific area Química Medicinal
Mode of delivery Face-to-face.
Work placements Not applicable
Learning outcomes On successful completion of this course unit it is expected that students will be able to describe and integrate the knowledge concerning the organs, cells and molecules of the immune system, their organization and diversity, including their specialized functions. By the end of this course the students must be able:
1.To describe the major events and aspects of the structure, dynamics, and functions of the human Immune System;
2.To describe the cells, molecules and pathways involved in the induction and regulation of normal innate and adaptive immune responses;
3.To understand the rational related with the main techniques used in routine analysis and in research and their practical application,
4.To develop the reading, interpretation and presentation capacities of research papers.
5.To improve the ability of solve problems in team.
1.Dynamics of the Immune System
2.Components of the Immune System
3.Inate Immunity
2.1. NK cells and phagocytic cells: characteristics, activation and function
2.2 Inflammation and Complement System
4.Structure and function of MHC-I and -II and antigenic presentation pathways
5.Cell-mediated Immunity: ontogeny and activation of T cells
5.1 Phenotypic and functional aspects of T cell populations
6.Humoral Immunity
5.1.Ontogeny and B cell activation
5.2.Immunoglobulins (Igs): diversity, characteristics, functions, isotype switching and affinity maturation
7.Central and peripheral Immune tolerance
1.Blood leuocytes morfology, their isolation and determination of cell concentration and viability
2.Techniques based on the interaction Antigen-Antibody
3.Histology of lymphoid tissues
Main Bibliography Main bibliography:
A.“Fundamentos de Imunologia” (2007) F. Arosa, E. Cardoso, F. Pacheco (Coord.), Lidel
B.“Color atlas of Cytology, Histology, and Microscopy Anatomy” (2003), cap. Blood and Immune system. Wolfgang Kuehnel, Thieme
C.“Imunologia- texto e atlas” (1998), cap. Aplicações laboratoriais. Burmester e Pezzutto, Lidel
Language Portuguese. Tutorial support is available in English.
Last updated on: 2012-05-21

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