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Bioactive Natural Products

Code 10267
Year 3
Semester S2
ECTS Credits 6
Workload PL(30H)/T(30H)
Scientific area Química Medicinal
Mode of delivery Presence
Work placements N/A
Learning outcomes This course aims at learning the aspects and uses of bioactive natural products, including their identification and isolation, chemical structure, the origin and application of biogenetic compounds. Faced with a concrete practical problem of a compound, the student will have the ability to analyze and consider the various plausible hypotheses, and among these, choose the best solution in terms of efficiency, economically and ease of implementation in terms of physical facilities available. Students deepen their practical knowledge of laboratory performance and characterization of chemical compounds.
Syllabus 1 - General Considerations
2 - Mechanistic Processes of Metabolism
3 - Medicinal Natural Products
4 – Terpenes, biosynthesis and biosynthesis
5 –Natural Compounds with nitrogen atoms
6 - Chemistry and Biology of Natural Antibiotic
7 - Bioactive Marine Natural Products
Main Bibliography P. M. Dewick, Medicinal Natural Products, A Biosynthetic Approach (2ª ed), Jonh Wiley and Sons, 2002
Colegate and Russell J. Molyneux, Bioactive Natural Products. Detection, Isolation, and Structural Determination. 2nd Edition. Edited by Steven M., CRC Press, Taylor and Francis Group, Boca Raton, 2008.
Xiao-Tian Liang Wei-Shuo Fang, Medicinal Chemistry of Bioactive Natural Products, John Wiley & Sons, Inc. 2006.
Newman, D. J.; Cragg, G. M.; Snader, K. M., The Influence of Natural Products Upon Drug Discovery. Nat. Prod. Rep., 17, 215-234, 2000.
Pilar G. Ruiz; Productos Naturales; Universidad Publica de Navarra, Ed: Universidad Publica de Navarra, 2002. España
J. Alberto Marco; Química de los Productos Naturales; Ed: SINTESIS, 2006, España
Goutam Brahmachari; Handbook of Pharmaceutical Natural Products, Ed: Wiley-VCH, 2010,
Language Portuguese. Tutorial support is available in English.
Last updated on: 2012-05-21

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