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General and Ocular Pharmacology

Code 12401
Year 1
Semester S1
ECTS Credits 6
Workload PL(15H)/TP(45H)
Scientific area Biomedical Sciences
Entry requirements To have basic knowledge on Cellular and Molecular Biology, General and Ocular Pharmacology and General Chemistry.
Learning outcomes -to know the general principles of pharmacology, classification and characteristics of the various types of drugs and their association with deviations from normal health parameters.
-to know the classification and characteristics of the main drugs and other ocular interfering agents.
-to interpret pharmacological and toxicological data of the main drugs used in the diagnosis, prevention and treatment of eye conditions.
-to identify and characterize the different dosage forms and routes of administration of drugs and other agents used in the prevention and treatment of eye conditions and in diagnostic tests and visual examinations.
-to evaluate the indication, apply and monitor the effects of diagnostic eye medications.
-to describe, justify and apply the criteria governing the rational use of eye agents as well as apply the necessary procedures for detecting eye adverse reactions and establish a course of action against them
Syllabus -Definitions and general principles, main pharmaceutical, pharmacokinetic and pharmacodynamic aspects and common systemic effects of drugs
-Major drug families - mechanisms of action, pharmacokinetic aspects, adverse reactions and other relevant characteristics

Ocular Pharmacology
-General principles, ocular pharmacokinetics, formulations and ophthalmic release of ocular agents
-Evaluation of ophthalmic patients: general health aspects and deviations from normal health parameters
-Drugs and other eye agents - classification, mechanism of action and pharmacokinetic characteristics, dosage forms and routes of administration, main indications, rational use and adverse reactions
-Toxicology and pharmacovigilance

Laboratory:
-Search for information on general and ocular drug toxicology
-Obtention and analysis of pharmacokinetic and pharmacodynamic parameters
-Dosage forms and posology and requirements for topical eye preparations
-Patho-pharmacological assessment in ocular diagnosis
Main Bibliography Basic:
-Rang & Dale's Pharmacology, H.P. Rang, J.M. Ritter, R.J. Flower, G. Henderson, 7th Edition, Elsevier, 2012, ISBN: 9780702034718.
-Clinical Ocular Pharmacology, J.D. Bartlett and S.D. Jaanus, 5th Edition, Elsevier, 2008, ISBN: 9780750675765.
Complementar:
-Goodman and Gilman's The Pharmacological Basis of Therapeutics, L. Brunton, B. Chabner, B. Knollman, 12th Edition, McGraw Hill, 2011, ISBN-13: 978-0071624428.
- Drug-Induced Ocular Side Effects, F. Fraunfelder, F. Fraunfelder, W. Chambers, 7th Edition, Elsevier, 2014, ISBN: 9780323319843
-Ocular Pharmacology and Toxicology, Ed: B.C. Gilger, Humana Press - Springer, 2014, ISBN: 978-1-62703-744-0.
Teaching Methodologies and Assessment Criteria There will be 3 TP frequencies and 1 PL frequency, and there will be evaluated the participation/attitudes of the student throughout the classe

Score = 0.25xNote 1st Freq.TP + 0.25xNote 2nd Freq.TP + 0.225xNote 3rd Freq.TP + 0.025xNote participation/attitudes in TP classes + 0.025xNote participation/attitudes in PL classes + 0.225xNote of PL frequency

The student must have the minimum attendance required, perform all laboratory work, perform all frequencies and achieve the minimum grade of 6 values to grant frequency and be admitted to examination (75% part TP + 25% part PL).
Language Portuguese. Tutorial support is available in English.
Last updated on: 2020-01-17

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