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Cellular Biology and Histology

Code 12495
Year 1
Semester S1
ECTS Credits 6
Workload PL(30H)/TP(30H)
Scientific area Biomedical Sciences
Entry requirements No requirements.
Learning outcomes To demonstrate fundamental knowledge about the function of cellular organelles, chemical composition, structure and properties of biomolecules and demonstrate knowledge of the processes and mechanisms of life at the molecular and cellular level. Knowledge of anatomy and histology as well as of human physiology should be demonstrated.
Syllabus Theoretical-practical classes (TP):
(1) cells (membranes, compartments, organelles, stem cells, cell differentiation)
(2) tissues (epithelium, glands, connective tissue, muscles, blood and nerves)
(3) Molecular biology (DNA, RNA, genetic code, DNA replication, protein synthesis)
(4) Bioenergy (ATP and ADP, free energy, glycolysis, Krebs cycle, oxidative phosphorylation, the role of oxygen)
(5) Retina, rhodopsin and neuronal pathways of vision.
Laboratory classes (PL): protein and amino acid determination, spectrophotometric methods, amino acids, DNA extraction, microscopy and mitotic phases.
Main Bibliography - Biologia Celular e Molecular, Carlos Azevedo, 4a edição, Lidel, edições técnicas, Lisboa, 2005.
- Molecular Cell Biology, Lodish et al., 5th edition, W. H. Freeman and Company, 2004.
- Molecular Biology of the Cell, Alberts et al, 3th or 4th Edition, Garland Publishing.
Teaching Methodologies and Assessment Criteria TP and PL classes in person. The final classification of the teaching-learning period (CEA) is calculated according to the following expression: CEA = 65% TP + 35% PL where, (TP) corresponds to the classification obtained in the theoretical-practical component, defined by two frequencies ( F1 and F2) and calculated according to the following expression: TP = 50% F1+ 50% F2. The practical laboratory component (PL) is determined according to the following expression: PL = 60% EP + 35% DL + 5% (P) where, (EP) corresponds to the classification obtained in the practical test (0 to 20 values), (DL) to the classification obtained in laboratory performance (0 to 20 values), (P) to punctuality (0 to 20 values). A final TP classification equal to or greater than 9.5 (arithmetic average of the two theoretical tests) is required to pass the theoretical component. A final PL grade equal to or greater than 9.5 is required to pass the curricular unit.
Language Portuguese. Tutorial support is available in English.
Last updated on: 2024-01-16

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