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Tissue Engineering

Code 12881
Year 1
Semester S2
ECTS Credits 6
Workload T(30H)/TP(30H)
Scientific area Bioengenharia
Entry requirements Not applicable
Mode of delivery Face-to-face
Work placements Not applicable
Learning outcomes This course unit gives to the students an overview about the structure, function, properties and production of materials used in tissue engineering. At the end of this course unit students must be able to:

- Recognise the importance of developing new biomaterials with appropiated properties to their application in tissue engineering.
- Know the different stages of biomaterials certification for their use in the clinical environment.
- Manipulate basic laboratory equipment.
- Collect, systematize and organize information in order to be aware to discuss a specific theme.
- Recognize their limitations and be aware of the importance of keeping their skills update.
paying special attention to self-learning based on scientific data available.
- Communicate orally and know how to write technical scientific documents.
Syllabus Theoretical program of the course unit

1. Fundamentals of tissue engineering
2. Biomaterials: definition, structure, properties and applications.
3. Biomaterials properties to be used in tissue engineering.
4. Mechanism of tissue growth and differentiation.
5. Tissue culture.
6. Cell and tissue transplantation.
7. Gene therapy.
8. Tissue engineering applied to the different organs of the human body.
9. Organogenesis

Practical programme of of the course unit

- Cell culture in vitro.
- In vitro and in vivo evaluation of materials cytotoxicity
- Acquisition of SEM images.
Main Bibliography Primary bibliography

1.Buddy D. Ratner, Allan Hoffman, Frederick Schoen, Jack Lemons, “Biomaterials Science. An Introduction to
Materials in Medicine” , Elsevier, 3rd Ed.(2012)
2.Myer Kutz,“Handbook of Materials Selection”, John Wiley & Sons (2001)
3.Scott A.Guelcher, Jeffrey O. Hollinger,“An introduction to Biomaterials” CRC Press (2006)
4.John P. Fisher , Antonios G.Mikos , Joseph D. Bronzino "Tissue Engineering",CRC Press (2007)

Supplementary bibliography

- Scientific articles
Teaching Methodologies and Assessment Criteria In this subject the teaching-learning activities are distributed in theoretical and practical classes. The teacher
promotes a great interaction with students in order to ensure their participation and motivation.
Pedagogical methods:
- Theoretical classes involve lectures where different themes are presented;
- In the practical lessons students perform different experimental protocols under the supervision of the
teacher, allowing the consolidation of knowledges tought in the theoretical classes and also the acquisition of
practical skills
- Students oral presentations based on scientific articles.

Assessment:
Final Grade: 80% exam+ 20% Oral presentations
- To be admitted to the final exam, students must have a final grade of at least 6 values.
Language Portuguese. Tutorial support is available in English.
Last updated on: 2020-05-14

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