Neurobiology

Code	13533
Year	1
Semester	S2
ECTS Credits	6
Workload	TP(60H)
Scientific area	Biomedical Sciences
Entry requirements	None
Mode of delivery	Face-to-face
Work placements	Not applicable
Learning outcomes	At the end of the course the student should have - acquired knowledge on: The function of the constituent cells of the nervous system and on the mechanisms of neuronal communication. Experimental methods used in neuroscience. Provide basic concepts on neuroanatomy and the plasticity of the nervous system. Concepts: To know the cellular constitution of the nervous tissue and the forms of communication between the cells that constitute the nervous system. Integrate knowledge about the basic mechanisms of functioning of the nervous system. Relate the changes associated with some pathologies of the nervous system with the basic neuronal mechanisms. Skills: Understand the fundamentals of different laboratory techniques and be able to develop an experimental protocol. Know how to analyze a scientific article. Know how to synthesize information and transmit it clearly and accurately to colleagues.
Syllabus	A- Biology of neural cells Neurons Synaptic transmission Axonal transport Synaptic plasticity and memory storage Neuronal and glial metabolism Glial cells Diverse functions of microglia and astrocytes - GB Neuroinflammation - GB Glymphatic system - GB Circadian changes in nervous system cells - TQ B- Neurotransmission Types of neurotransmitters; synthesis and storage; characteristics of release and termination of action. Alterations to neurotransmission in pathologies of the nervous system Amines (dopamine, noradrenaline, serotonin) Acetylcholine Glutamate & GABA Neuropeptides Practical activities: Development of experimental protocols with models used in neuroscience.
Main Bibliography	Neuroscience. Dale Purves, George J. Augustine, David Fitzpatrick , William C. Hall, Anthony-Samuel Lamantia, James O. McNamara , S. Mark Williams. Sinauer Associates. Neurobiology: Molecules, Cells and Systems. Gary G. Matthews. Blackwell Publishers. Basic Neurochemistry : Molecular, Cellular and Medical Aspects. George J. Siegel, R. Wayne Albers, Scott Brady, Donald L. Price. Academic Press.
Language	Portuguese. Tutorial support is available in English.