| Code |
13539
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| Year |
1
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| Semester |
S1
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| ECTS Credits |
6
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| Workload |
PL(30H)/T(30H)
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| Scientific area |
Biochemistry
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|
Entry requirements |
Not applicable
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Mode of delivery |
Face-to-face
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Work placements |
Not applicable
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Learning outcomes |
This course unit gives to the students an overview of the fundamental unit of life: the cell
(structure, function of the different cellular compartments, cell activation pathways, cell cycle,
cell renewal and apoptosis).
At the end of this course unit students must be able to:
- Be aware that cells are the morphological and functional units of living beings.
- Describe the main cellular signaling pathways.
- Know the mechanisms through which cells regulate their cell cycle.
- Know and apply the laboratory safety rules.
- Manipulate basic laboratory equipments.
- Read and understand scientific documents.
- Be creative and capable to adapt to new professional situations.
- Recognize their limitations and be aware of the importance of keeping their skills update,
paying special attention to self-learning based on scientific data available.
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Syllabus |
Theoretical program
1. Introduction to Molecular Cell Biology
1.1 The cell: the morphological and functional unit of living beings
1.2 Endosymbiotic Theory
2. Cell nucleus: structure and functions
3. Structure and function of cellular organelles
4. Cell cytoskeleton: structure and function
5. Cellular signalling pathways
5.1 Membrane Receptors
5.2 Proteins involved in cellular signalling
5.3 Second messengers
6. Cell cycle
6.1 Apoptosis
7. Characterization of cell adhesion to the extracellular matrix
8. Introduction to tissues: structure and function
8.1 Epithelial Tissue
8.2 Connective Tissue
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Main Bibliography |
1. Main Bibliography
- Biologia celular e molecular, Carlos Azevedo, 5ª edição, Lidel, Edições Técnicas, Lisboa, 2012.
- Alberts B., Bray D., Hopkin K. et al, “Fundamentos de Biologia Celular”. 3th Ed. Artmed, 2011.
- Molecular cell biology, lodish et al., 9th edition, New York : Macmillan Learning, 2021.
- Karp's Cell and Molecular Biology: Concepts and Experiments, 8th Edition, john wiley & sons, inc., 2016.
2. Complementary bibliography
- http://www.ncbi.nlm.nih.gov/pubmed/
- http://www.rcsb.org/pdb/home/home.do
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Teaching Methodologies and Assessment Criteria |
The teacher makes the oral exposure of the different contents using slides in the theoretical lectures. During classes students are stimulated to discuss the various themes with teacher and colleagues.
In practical classes students learn how to do online bibliographic search and to use informatic tools to observe nucleic acids and proteins, under teacher supervision. Students have also the opportunity to learn basic techniques used in research laboratories and lab safety rules.
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Language |
Portuguese. Tutorial support is available in English.
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