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Pharmacognosia I

Code 13640
Year 1
Semester S2
ECTS Credits 6
Workload PL(30H)/T(30H)
Scientific area Ciências Farmacêuticas
Entry requirements None.
Mode of delivery face-to-face
Work placements Not applicable
Learning outcomes At the end of the course unit the student should be able to: know some notions of plant biology and physiology; identify medicinal plants and relate them with their chemical and biological properties; relate the active ingredients and their therapeutic interest; identify the phytopharmaceutical products according to their therapeutic uses, toxicity and possible interactions with other drugs; analyze the natural compounds regarding the extraction and isolation methods used and provide identification of active compounds; know the plant constituents synthesized via the primary metabolism.
Syllabus Theoretical contents: Major taxonomic groups. Plant cell. Cell walls of plants, fungi and bacteria. Primary and secondary metabolism. Plant anatomy and histology. Interest of plant raw materials in the pharmaceutical industry, production and conversion to drugs. Main plant constituents derived from the primary metabolism – Carbohydrates: simple sugars, oligosaccharides, polysaccharides. Plant Lipids. Compounds with nitrogen. Laboratorial contents: Observation of plant cells.Plant anatomy. Isolation of chloroplasts. Determination of pigments in wine by Folin-Ciocalteu index. Research of reducing and non-reducing sugars (Fehling test) // Determination of gums and exudates swelling index. Thin-layer chromatography of a sugar mixture. Evaluation of honey samples. Determination of chemical analytical indexes in fatty drugs. Isolation of trimyristin from nutmeg.
Main Bibliography Pharmacognosie, phytochimie, plantes médicinales, Bruneton, J., Editions Techniques et Documentation, 3eme edition, 1999.
Farmacognosia e fitoquímica , Proença da Cunha, A. (Ed.), Fundação Calouste Gulbenkian, 2005.
Trease and Evans Pharmacognosy, Evans, W.C., Edinburgh: Saunders , 2002.
Farmacopeia Portuguesa, 1º e 2º vol., 9ª Ed oficial, Ministério da Saúde, INFARMED, 2008.
Farmacognosia - Farmacognosia experimental, Costa, A. F., Fundação Calouste Gulbenkian, 3ª ed., 2001.
Biologia Vegetal, Raven, H.P.; Evert, R.F.; Eichhorn, S.E. 8ª ed., Ed. Guanabara Koogan, Rio de Janeiro,1996.

Language Portuguese. Tutorial support is available in English.
Last updated on: 2021-06-24

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