| Code |
13655
|
| Year |
3
|
| Semester |
A1
|
| ECTS Credits |
14
|
| Workload |
PL(60H)/T(30H)/TP(90H)
|
| Scientific area |
Ciências Farmacêuticas
|
|
Entry requirements |
To be a UBI pharmaceutical sciences student
|
|
Mode of delivery |
tutorial
|
|
Work placements |
The work placement is included in the programme of interim stages of the general curricular plan
|
|
Learning outcomes |
Study in an integrated way the therapeutics and diagnosis of various infectious processes produced by bacteria, fungi, parasites, and viruses that can occur to a human level
At the end of this course unit the student will be able to:
- Know, how to apply the principles of general pharmacology on pharmacology of infection.
- Describe and discuss bacterial infections, fungal infections, parasites and viral infections.
-Identify key groups of molecules used against infections
- Describe and recognise the symptoms of major infectious diseases
-Run the laboratory diagnostic tests of the main infectious diseases
- Choose the therapy of the main infectious diseases
- Analyze structure-activity relationship.
|
|
Syllabus |
Introduction to the pharmacology of infection. Major groups of molecules used against bacterial infections, fungal infections, parasites and viral infections: mechanisms of action, resistance mechanisms, pharmacokinetic parameters and side effects. Symptoms and laboratory diagnostic tests of the main pathologies produced by bacteria, fungi, parasites and viruses. Basic clinical factors for the election of an anti-infective treatment. Treatment of major infectious diseases caused by bacteria, fungi, parasites and viruses. Systematic study of several groups of drugs. Structure-Activity Relationships.
|
|
Main Bibliography |
Integrated Pharmacology – Dale – Secção I e capitulo 9 da secção 2 The Pharmacological Basis of therapeutics – Goodman and Gilman – (9ª ed.) Pharmacology – Rang ( 5ª edição)–cap. 44 e 45 João Carlos de Sousa, Manual de Antibióticos Antibacterianos , 2th edição. Foye´s Principles of Medicinal Chemistry, 5th Ed., D.A. Williams; T.L. Lemke, Lippincort Williams & Wilkins, 2002 Introducción a la Química Farmacéutica, 2ª Ed., C. Avendaño, Mc-Graw-Hill, 2001 – Medicinal Chemistry-A Molecular and Biochemical Approach, 3rd Ed., T. Nogrady, D.F. Weaver, Oxford University Press, 2005 – The Organic Chemistry of Drug Design and Drug Action, 2nd Ed., R.B. Silverman, Elsevier Academic Press, 2004 – Chemistry for Pharmacy Students, S.D. Sarker, L. Nahar, Wiley, 2007 – Patrick. Murray, Medical Microbiology PRESCOTT, HARLEY & KLEIN. Microbiology. Seventh edition, Wm. C. Brown-McGraw-Hill Publishers, 2007 Clinical Pharmacy and therapeutics, 5th edition – by Roger Walker and Cate Whittlesea , 2012
|
|
Teaching Methodologies and Assessment Criteria |
The teaching learning process is organized in theoretical and theo-practical tutorials and laboratorial activities. In class tutorials all contents are developed through the analysis and discussion of papers/slides/chapters of books and by solving problems. The program is divided into 8 themes and for each theme exists a laboratory activity in which the main objective is the integration of the knowledge acquired in the tutorials and the acquisition of skills on microbiology, virology, Mycology and Parasitology laboratory practices.
The evaluation is continuous and summative: theoretical knowledge (A = 0 to 14), practical knowledge (B = 0 to 4), and laboratory skills (C = 0 to 2).
|
|
Language |
Portuguese. Tutorial support is available in English.
|