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Human Pathophysiology and Pharmacology

Code 13656
Year 3
Semester A1
ECTS Credits 20
Workload PL(60H)/TP(200H)
Scientific area Ciências Farmacêuticas
Entry requirements N.A.
Mode of delivery The sessions are daytime and attending with small groups of students. The topics are organized in Pedagogic Units (PU) with continuous evaluation along the year.
Work placements Not applicable.
Learning outcomes 1) To explain the diseases pathophysiology
2) To understand the drug actions as modifiers of the pathophysiology mechanisms of the diseases and the drugs structure-activity relationship.
3) To recognize the link between the disease pathophysiology and the clinical biochemical parameters


a) To be able to apply the knowledge and the understanding capacity acquired in order to have a professional approach concerning the diseases, the diagnosis and the treatment.
b) To have the capacity to collet, to select and to comprehend the relevant information concerning drugs, diseases and clinic analysis.
c) To be able to communicate ideas, information, problems and solutions related with the drugs and clinic analysis either to health specialists or to the health system users.
d) To have competences to allow a lifetime and autonomous learning about the imparted discipline.
Syllabus PU1: Basic pathophysiology. Basic Pharmacodynamics and Pharmacokinetics. Basic principles of biochemical clinic analysis.
PU2: Mechanism participating and drugs used in inflammation, fever e pain. Anaesthetic drugs. Drugs used in transplant and autoimmune diseases.
PU3: Drugs acting in the peripheral nervous system. Neuromuscular diseases. Spasmolytic.
PU4: Central nervous system diseases and used drugs.
PU5: Drugs used to treat cardiovascular and renal diseases. Analytics used to make diagnosis of these diseases.
PU6: Drugs used to treat respiratory and digestive diseases. Analytics used to make diagnosis of these diseases.
PU7: Drugs used to treat metabolic and endocrinology system pathologies. Analytics used to make diagnosis of these diseases.
PU8: Drugs used to treat pathologies related with neoplastic growth, blood or immune system. Analytics used to make diagnosis of these diseases.
Main Bibliography Avendaño C (2001). Introducción a la Química Farmacéutica, McGraw-Hill
Burtis CA et al. (2008) Tietz Fundamentals of Clinical Chemistry
De Castro (2006). Manual de Patologia General. Masson
Fulcher EM (2012). Farmacology: Principles and applications. Elsevier.
Lullmann H (2000). Color Atlas of Pharmacology. Thieme.
Guimarães, Moura & Silva (2006). Terapêutica Medicamentosa e suas Bases Farmacológicas. Porto Editora
Mattson C (2010). Essentials of Patophysiology. Lippincott Williams & Wilkins.
Memmler (2005). The human body in heath and disease. Lippincott Williams & Wilkins.
McPhee (2009). Pathophysiology of Disease. McGraw-Hill Medical
McPherson RA et al. (2011). Henry''s Clinical Diagnosis and Management by Laboratory Methods. Saunders.
Puri BK (2011). Textbook of psychiatry. Churchill Livingstone.
Williams DA et al.(2002). Foye´s Principles of Medicinal Chemistry. Lippincort Williams & Wilkins.
Rang & Dale (2011). Pharmacology. Churchill Livingstone.
Teaching Methodologies and Assessment Criteria a) Pedagogic methodology centred in the student. The participation of the student in the learning process allows a higher development of his reasoning capabilities, self-learning and selfevaluation.
b) Learning involving the integration of different basic scientific areas and also clinical areas related with pathology.
c) Organisation of the learning topics by pedagogic Unites (PU) and performing of continuous evaluation along the year.
d) Learning activities in small groups of students and using convenient resources to achieve selflearning and to have a personalized follow-up along all the process.

Language Portuguese. Tutorial support is available in English.
Last updated on: 2021-06-14

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