| Code |
13694
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| Year |
4
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| Semester |
S2
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| ECTS Credits |
3
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| Workload |
TP(30H)
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| Scientific area |
Physics and Chemistry
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Entry requirements |
Not applicable
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Learning outcomes |
At the end of this course unit, the student should be able to:
(i) describe the organization and operation of a clinical analysis laboratory;
(ii) identify the main analytes and laboratory methods used in hematology, immunochemistry, microbiology, and immunology;
(iii) interpret relevant laboratory results within the pathophysiological context of major diseases;
(iv) relate analytical results to disease diagnosis, prognosis, and monitoring;
(v) recognize the principles of quality control, biopathological validation, and laboratory safety.
These objectives are achieved through theoretical and theoretical-practical classes, discussion of clinical cases, and contact with the reality of hospital laboratory practice, promoting the integration of laboratory knowledge with clinical interpretation.
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Syllabus |
1. Organization of the clinical laboratory and types of biological samples.
2. Hematology: cytometry, complete blood count, peripheral blood cells, erythrocyte, leukocyte and platelet disorders; hemostasis, coagulation and fibrinolysis; hemoglobin A1c and clinical relevance.
3. Immunochemistry: substrates and enzymes, cardiac markers, tumor markers, endocrinology, plasma proteins, urinalysis, drugs, drugs of abuse and blood gas analysis.
4. Microbiology: detection and identification of microorganisms, antibiogram and antimicrobial resistance.
5. Immunology: autoimmune diseases, specific IgE and infectious serology.
6. Transversal disciplines: flow cytometry, molecular biology, laboratory methods, internal quality control and external quality assessment, epidemiology and laboratory semiotics.
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Main Bibliography |
McPherson RA; Pincus MR.
Henry’s Clinical Diagnosis and Management by Laboratory Methods, 24th Edition.
Saunders, Elsevier (2022).
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Teaching Methodologies and Assessment Criteria |
Assessment is carried out through a midterm test or a final exam, consisting of a 90-minute written multiple-choice test.
A minimum grade of 10/20 is required to pass.
Students may choose to take only the final exam, with no minimum midterm grade required for exam admission.
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Language |
Portuguese. Tutorial support is available in English.
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