This Curricular Unit (UC) aims to provide, in a pharmaceutical perspective, current knowledge about new synthetic processes and their application in the laboratory and industrial preparation of molecules of therapeutic interest and/or their synthesis intermediates. At the end of the course, it is intended that the student knows how to apply the (Pharmaceutical) Green Chemistry metrics and how to evaluate the processes for the chemical preparation of drugs. In addition, the student should know how to develop and apply new synthetic processes with interest in the Pharmaceutical Chemical Industry, especially in the preparation of “Active Pharmaceutical Ingredients ”(APIs).
-Green Techniques for Organic Synthesis and Medicinal Chemistry, Wei Zhang, and Berkeley W. Cue (Editors), Wiley, 2012.
-Green Chemistry in the Pharmaceutical Industry, Peter J. Dunn, Andrew S. Wells, and Michael T. William (Editors), WileyVCH, 2010.
-EcoFriendly Synthesis of Fine Chemicals, Roberto Ballini (Editor), RSC, 2009.
-J.A.R. Salvador, R.M.A. Pinto, S.M. Silvestre, “Pharmaceutical Green Chemistry Applied to the Chemical Synthesis of Steroid Compounds”, Current Green Chemistry, 2015, 2(2): 97134.
-R.M.A. Pinto, S.M. Silvestre, “Pharmaceutical Green Chemistry: Is Just Green Chemistry or Is Something Else More?”, Journal of Chemical Engineering and Chemistry Research, 2014, 1(5): 290301.
-Outros artigos de revistas científicas