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Endocrine System and Metabolism

Code 15120
Year 2
Semester A1
ECTS Credits 7
Workload OT(64H)/PL(6H)/S(2H)/TP(8H)
Scientific area Morphological and Functional Sciences
Entry requirements Not applicable
Learning outcomes Provide students with in-depth knowledge of the endocrine and metabolic system through an integrated approach to the anatomy, physiology, histology, embryology and biochemistry of this system.
At the end of the course unit the learner is expected to be able to
- integrate the knowledge of endocrinology with those acquired in previous periods of their training, cellular and molecular mechanisms;
- describe the microscopic and macroscopic morphology of the endocrine system and its embryonic development;
- characterize the endocrine system relating the chemical structure of hormones with the functions they perform.
- interpret the action of hormones in the regulation of carbohydrates, lipids and nitrogen compounds metabolism and calcium and phosphorus homeostasis;
- interpret clinical problems related to the endocrine system functioning;
- work in team in the resolution of problems and in the acquisition of knowledge.
Syllabus FUNCTIONAL ORGANIZATION OF THE ENDOCRINE SYSTEM
Types of hormones.
Hypothalamic-pituitary axis.
Macroscopic and microscopic morphology of thyroid and parathyroid glands, adrenals and pancreas and their hormones.
NUTRITION AND METABOLISM. REGULATION OF CARBOHYDRATES METABOLISM.
Hormonal regulation of metabolic rate.
Importance of temperature control and body mass for the human body.
Hormonal regulation of glycolysis, gluconeogenesis and glycogen metabolism.
Control of glycemia and tissues involved.
Physiological relevance of the pentose phosphate pathway.
REGULATION OF LIPID AND NITROGEN METABOLISM. METABOLIC INTEGRATION
Hormonal regulation of lipid transport and storage.
Hormonal regulation of lipid synthesis and degradation, metabolism of ketone bodies, cholesterol metabolism and urea cycle in human protein metabolism.
Operation of the different metabolic pathways in periods after meals and in periods of fasting.
HORMONAL CONTROL OF GROWTH.
HORMONAL REGULATION OF MINERAL METABOLISM.
Main Bibliography BIBLIOGRAFIA PRINCIPAL
• BERNE RM, LEVY MN (2017). Physiology. 7th edition. Philadelphia, Mosby/Elsevier.
• Widmaier, E. P., Raff, H., Strang, K. T., & Vander, A. J. (2019). Vander's human physiology: The mechanisms of body function. 15th Edition. Boston, MA: McGraw-Hill.
• Gardner, D. G., Shoback, D. M. (2018). Greenspan's basic & clinical endocrinology. 10th Edition. New York, McGraw-Hill.
• Rodwell, V. W., Bender, D. A., Botham, K. M., Kennelly, P. J., & Weil, P. A. (2018). Harper's illustrated biochemistry. 31st edition. New York, McGraw-Hill.

BIBLIOGRAFIA COMPLEMENTAR
Antonino Belfioread and Derek LeRoith (2018): Principles of Endocrinology and Hormone Action. Springer International Publishing
Guyton, A. & Hall, J. (2020). Textbook of Medical Physiology. 14th Edition. Philadelphia, Saunders/Elsevier.
Language Portuguese. Tutorial support is available in English.
Last updated on: 2025-09-28

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