| Code |
15126
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| Year |
3
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| Semester |
A1
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| ECTS Credits |
5
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| Workload |
OT(70H)
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| Scientific area |
Biopathological Sciences
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Entry requirements |
NA
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Learning outcomes |
The course unit "Therapeutic Foundations" aims to provide students with fundamental knowledge of pharmacology and its application in rational and multimodal therapeutic planning. By the end of the course, students should be able to understand general mechanisms of drug action and key pharmacodynamic and pharmacokinetic parameters, identify relevant adverse effects and drug interactions, know the therapeutic applications and mechanisms of action of major pharmacological classes, apply acquired knowledge to solve clinical problems and define evidence-based therapeutic strategies, develop self-learning skills, critical thinking, and individual responsibility, use principles of Evidence-Based Medicine in rational drug selection, and integrate knowledge acquired throughout the course into clinical practice.
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Syllabus |
1. General principles of pharmacology: pharmacokinetics, pharmacodynamics, interactions, adverse reactions, and toxic effects
2. Neurotransmission and neuromodulation
3. Neuropharmacology of the autonomic nervous system
4. Neuropharmacology of the central nervous system
5. Pharmacotherapy of the main biological systems (cardiovascular, respiratory, digestive, endocrine)
6. Antibacterials, antiretrovirals, and antifungals
7. Clinical studies and rational drug selection
8. Discussion of clinical cases and use of guidelines
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Main Bibliography |
• Rang & Dale's Pharmacology. 10th Edition. James M. Ritter, Rod Flower; Graem Henderson, Yoon Kong Loke, David MacEwan, Emma Robinson e James Fullerton. 2025. Elsevier
• Goodman & Gilman's - The Pharmacological Basis of Therapeutics. 14th Edition. 2023. McGraw Hill LLC
• Guidelines terapêuticas nacionais e internacionais (DGS, EMA, NICE, etc.)
• Bases de dados: Infomed, Micromedex, UpToDate, PubMed
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Teaching Methodologies and Assessment Criteria |
Assessment is conducted on a scale of 0 to 200 points corresponding to 20 "valores".
It includes four on-site tests without consultation (UP1–UP6), a Global Test based on clinical cases, and three online guideline-application quizzes. On-site tests include multiple-choice, multiple-response, and short-answer questions. Online tests are essentially formative.
Attendance is granted with a minimum score of 6 and completion of all components.
Passing requires a minimum score of 10.
The final exam covers all taught components and is closed-book.
Passing the exam requires a minimum score of 10.
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Language |
Portuguese. Tutorial support is available in English.
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