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Learning outcomes |
In this curricular unit it is intended that the student acquires knowledge in the field of structural analysis of organic compounds, with known or unknown structure, using various spectroscopic techniques, in particular, IR spectroscopy, UV-vis., H NMR, C and Two-Dimensional and mass spectrometry.
At the end of this CU students must:
-Know the fundamentals of different spectroscopic techniques;
-In IR spectroscopy, know the interactions and types of connections that produce the different absorptions and identify functional groups;
-In UV-vis spectroscopy, define the different absorption systems, chromophores, conjugated systems and aromatic;
-Apply H-NMR and C. Know what is chemical shift and splitting of the signal;
-Apply two-dimensional correlation-H - H, H - C, for structural determination;
-Know mass spectrometry and the concepts molecular ion, molecular formula, base peak and fragmentation;
-Apply the different methods for structure assignment.
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Main Bibliography |
-Holzgrabe, U., Diehl B., Wawer, I. “NMR Spectroscopy in Pharmaceutical Analysis” 2008, Elsevier, Netherlands
Gunther, H., “NMR Spectroscopy: Basic Principles, Concepts and Applications in Chemistry” 2013, 3rd Ed., Wiley VCH
-Macomber, R.S., “A Complete Introduction to Modern NMR Spectroscopy” 1998, John Wiley & Sons Inc., Canada
-Balci, M., “Basic 1H- and 13C-NMR Spectroscopy” 2005, Elsevier, Netherlands
-Anderson, R.J. et al “Organic Spectroscopic Analysis” (2004), RSC, UK
-Shriner, R.L., Hermann, C.K.F., Morrill, T.C., Curtin, D.Y., “The Systematic Identification of Organic Compounds” 2004, 8th Ed.; John Wiley & Sons.
-Manfred, H., Herbert, M., Bernd, Z., “Métodos Espectroscópicos en Química Orgánica” 2005, 2º Ed.; Ed. Sintesis.
-Maurer, H.H., Pfleger, K., Weber; A. A., “Mass Spectral and GC Data of Drugs, Poisons, Pesticides, Pollutants and Their Metabolites” 2011, Wiley – VCH.
-Cullity, B.D., “Elements of X-ray Diffraction” (2001), 3rd Ed, Addison-Wesley, Reading, M.A.
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