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Mechanisms of Diseases

Code 16698
Year 3
Semester S1
ECTS Credits 6
Workload PL(30H)/TP(30H)
Scientific area Biomedical Sciences
Entry requirements NA
Learning outcomes Knowledge:
1. To integrate concepts regarding physiology and the homeostatic functioning of systems and transpose them to
genetic, biochemical, molecular, cellular, structural, and functional pathological mechanisms underlying human
diseases.
2. To identify epidemiological factors of disease.
3. To identify common and distinctive features of diseases.
4. To infer models, methodologies, and technologies used in scientific and therapeutic research on diseases.
5. To develop the ability to correlate scientific and translational information in pathophysiology, focusing on clinical
application.
Soft skills:
1. To develop critical thinking and perform logical-deductive reasoning in problem-solving.
2. To develop research skills.
3. To acquire oral and written communication skills.
4. To be able to translate fundamental science to biomedical and clinical applications.
5. To develop team cooperation skills.
Syllabus Theoretical-Practical (TP)
The main aim is to integrate the contents previously learned in other UC about the normal functioning of systems and
transpose them to the genetic, biochemical, molecular, cellular, structural, and functional mechanisms of diseases, as
well as translate them into biomedical and clinical applications, namely in the:
- cardiovascular system
- endocrine system
- nervous system
- immune system
Environmental pathology.
Laboratory practices (PL)
- In vitro and in vitro experimental models of diseases.
- Experimental and analytical methodologies used in the study of disease mechanisms.
Main Bibliography 1. Robbins, S.L., Cotran, R.S., Kumar, V. (2020). Pathologic basis of disease (10º ed). Elsevier.
2. McPhee, S.J., Ganong, W.F. (2018). Pathophysiology of Disease (8ª ed). McGraw-Hill
3. Original and review articles
Language Portuguese. Tutorial support is available in English.
Last updated on: 2025-12-24

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