| Code |
17236
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| Year |
1
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| Semester |
S2
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| ECTS Credits |
6
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| Workload |
PL(30H)/T(30H)
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| Scientific area |
Biochemistry
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|
Entry requirements |
None
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Mode of delivery |
Face-to-face
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Work placements |
Not applicable
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Learning outcomes |
At the end of the course the student should have
- acquired knowledge on:
The function of the constituent cells of the nervous system and on the mechanisms of neuronal communication.
Experimental methods used in neuroscience.
Provide basic concepts on neuroanatomy and the plasticity of the nervous system.
Concepts:
To know the cellular constitution of the nervous tissue and the forms of communication between the cells that constitute the nervous system.
Integrate knowledge about the basic mechanisms of functioning of the nervous system.
Relate the changes associated with some pathologies of the nervous system with the basic neuronal mechanisms.
Skills:
Understand the fundamentals of different laboratory techniques and be able to develop an experimental protocol.
Know how to analyze a scientific article.
Know how to synthesize information and transmit it clearly and accurately to colleagues.
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Syllabus |
THE BRAIN AS A CELLULAR ECOSYSTEM
Nervous tissue as an integrated system
Glia as an active regulator of neural function
Biological rhythms and brain clearance
ENERGY, EXCITABILITY, AND COMMUNICATION
4. Neuronal and glial metabolism
5. Synaptic transmission
6. Synaptic plasticity and memory storage
NEUROTRANSMISSION SYSTEMS AND NETWORK FUNCTION
7. Fundamentals of neurotransmission
8. Excitatory and inhibitory systems
9. Diffuse modulatory systems
DYSFUNCTION, INFLAMMATION, AND DISEASE
10. Neuroinflammation and network dysregulation
11. Synaptic dysfunction and cellular vulnerability
Practical activities: Development of experimental protocols with models used in neuroscience.
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Main Bibliography |
Neuroscience. Dale Purves, George J. Augustine, David Fitzpatrick , William C. Hall, Anthony-Samuel Lamantia, James O. McNamara , S. Mark Williams. Sinauer Associates.
Neurobiology: Molecules, Cells and Systems. Gary G. Matthews. Blackwell Publishers.
Basic Neurochemistry : Molecular, Cellular and Medical Aspects. George J. Siegel, R. Wayne Albers, Scott Brady, Donald L. Price. Academic Press.
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Language |
Portuguese. Tutorial support is available in English.
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