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Informatics Applied to Biological Sciences

Informatics Applied to Biological Sciences

Code	12476
Year	1
Semester	S1
ECTS Credits	6
Workload	PL(30H)/T(30H)
Scientific area	Biotecnologia
Entry requirements	Not applicable
Mode of delivery	Face-to-face
Work placements	Not applicable
Learning outcomes	The course aims to introduce students to different algorithms and computational techniques currently used in modern bioinformatics and its application to solving problems in biology and medicine, with emphasis on applications of molecular biology. To this end, students must achieve the following objectives: - Be aware of the most important biological databases and know how to extract information from these databases. - Understand the motivations, assumptions and limitations of computational techniques that are applied to solve a particular problem in biology. - Explore existing implementations of the most common algorithms for various computational problems and know how to parametrize them properly. - Identify research trends in bioinformatics.
Syllabus	1) Introduction to Bioinformatics; 2) Biological databases; 3) Sequence alignment algorithms; 4) Predictive algorithms; 5) Data analysis; 6) Application and research in Bioinformatics.
Main Bibliography	1. Required reading An Introduction to Bioinformatics Algorithms, N. C. Jones and P. Pevzner, MIT Press, 2004. Essential Bioinformatics, Jin Xiong Cambridge, University Press, 2006. Introduction to Bioinformatics, 2nd edition, Arthur M. Lesk, Oxford University Press, 2002. 2. Recommended reading Biological Sequence Analysis - Probabilistic Models of Proteins and Nucleic Acids, Richard Durbin, Sean R. Eddy, Anders Krogh and Graeme Mitchison, Cambridge University Press, 2004. Analyzing Microarray Gene Expression Data, Geoffrey J. Maclachlan, Kim Anh-Do and Christophe Ambroise , Wiley, 2004. Digital Code of Life, Glyn Moody, Wiley, 2004. Bioinformatics for Dummies, 2nd edition, Jean-Michel Claverie, Cedric Notredame, Wiley, 2006
Language	Portuguese. Tutorial support is available in English.