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Biotechnology and Innovation

Code 12481
Year 1
Semester S2
ECTS Credits 6
Workload TP(60H)
Scientific area Biotecnologia
Entry requirements -
Mode of delivery Classroom teaching
Work placements Not applicable
Learning outcomes The Course Unit allows students to acquire an overview of the different fields of biotechnology, as well as identify innovative approaches in this area. Thus, students should acquire the following knowledge / skills:
- To apply the concept of Biotechnology, with relation to the general objectives of development of products, processes or services.
- To identify and characterize the innovative methodologies designed to optimize each step of a biotechnological process, enhancing their integration and application at an industrial scale for the production of products of interest.
- To study current and innovative examples for the development and / or application of products or technologies in different areas of biotechnology.
Syllabus - Innovation in Biotechnological processes. Design and control of metabolic pathways of host systems. Proteomics and Metabolomics evaluation. Selective recovery methods. Magnetic particles and Ionic Liquids. Continuous Purification Technology and new media.

- Delivery and targeting systems. Nanometric systems. Encapsulation of drugs. Functionalization of delivery systems. Passive and active targeting. Case studies.

- Gene Therapy and Silencing Mechanisms. Gene Therapy, DNA vaccines and RNA interference mechanisms. Advances and Challenges of these new therapeutic approaches.

- Production of "Bio" Pigments in microorganisms. New generation of pigments produced by bacteria vs synthetic dyes. Production of bacterial pigments. Applications in the textile, food and pharmaceutical industry.

- Production processes for microalgae. Microalgae with greater technical and economic potential. Bioeconomy. Algal biomass production and extraction of products with application in the food, cosmetic and pharmaceutical industry.
Main Bibliography - Woollett, G R. Innovation in Biotechnology: Current and Future States. Clinical Pharmacology & Therapeutics. 2012. 91:17.
- Tuli H.S. et al. Microbial pigments as natural color sources: current trends and future perspectives. Journal of Food Science and Technology. 2015. 52: 4669
- Handbook of Microalgal Culture: Applied Phycology and Biotechnology, 2nd Edition, Amos Richmond and Qiang Hu (Editors), May 2013, Wiley-Blackwell, ISBN: 978-0-470-67389-8.
- Scientific articles.

Teaching Methodologies and Assessment Criteria - Tutorial classes and seminars with area experts to complement theoretical content and applications. The tutorial methodology allows a greater intervention and research activities on the part of the students in order to reach the proposed objectives, considering the recommended bibliography, with teacher orientation.
- Problem-based learning involving case studies.
- Two evaluations will be carried out in order to ascertain the degree of mastery of the transmitted material. The evaluation of the project to be carried out by the students will have as purpose to evaluate the capacity that they acquire to idealize a project with recourse to the creative use of the acquired knowledge.
Language Portuguese. Tutorial support is available in English.
Last updated on: 2021-03-08

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