Learning outcomes |
The unit of Biotechnology aims to provide students with a global perspective of biotechnological processes, with emphasis on the production and purification of biomolecules for therapeutic application. At the end of this course the student should be able to: -Describe the importance of Biotechnology in the current context and explain their applications, focusing on health. -Demonstrate an integrated view of bioprocesses, including the processes of production in bioreactors, isolation and purification of biomolecules and apply the techniques / unit operations used in different stages to obtain bioproducts for therapeutic applications with high yield and purity. -Demonstrate strategy and autonomy in making decisions regarding the resolution of concrete problems in Biotechnology, based on the scientific and technical capacity and critical thinking.
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Main Bibliography |
- Crommelin D.J. A., Sindelar, R D., Meibohm “Pharmaceutical Biotechnology: Fundamentals and Applications”, 3rd Edition, CRC Press, 2016. - Ho R. J. Y., Gibaldi, M “Biopharmaceutical Technologies and Processes in Drug Development”, Wiley, 2003. -Lima N, Mota M. (Eds) “Biotecnologia: Fundamentos e Aplicações”. Lidel, Lisboa, 2003. - Stanbury P., Whitaker, A. Hall, S. “Principles of Fermentation Technology” 3rd Edition, Butterworth-Heinemann, 2016. -Fonseca M M, Teixeira JA (Eds) “Reactores Biológicos-Fundamentos e Aplicações”, Lidel, 2007. -Nicholl, D “An Introduction to Genetic Engineering”, 3ª Ed., Cambridge, 2008, Pg. 51-89 e pg 202-225. -Blankenstein T, “Gene Therapy: Principles and Applications”, Birkhäuser Verlag, 2003. -Selected scientific papers
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Teaching Methodologies and Assessment Criteria |
A.1- The evaluation of TP modules corresponds to 70% of the final mark (FM) and includes 3 tests where it will be necessary to obtain an average minimum grade of 9.5 (Val) for approval to A1: 1st test: Mod 1: Mod 1:18 % + Mod 2: 24% . 2nd test: Mod 3: 24 % . 3rd Test: Mod 4: 34 % + Mod 5: 10 %
A.2 – Practical Assessment (15% of FM) in total of 4 practical works (20 pt): 1st test (5 pt), 2nd test (5 pt), 3rd test (includes 2 works: 5pt + 5 pt). Minimum grade of 9,5 pt for approval to A2.
A.3- The evaluation of the Seminar (15% of FM) includes a presentation and oral discussion of a scientific paper tried by a jury of Biotechnology professors, respecting an evaluation grid previously provided to the students. Minimum grade of 9,5 pt for approval to A3.
Frequency FM: 70% Mod TP + 15 % Mod PL + 15% Seminar The exam corresponds to Mod TP and/or Mod PL Exam FM: 70% Mod TP + 15 % Mod PL + 15% Seminar
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