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Chemical and Bological Analysis for Clinical Application

Code 12885
Year 1
Semester S2
ECTS Credits 6
Workload PL(30H)/T(30H)
Scientific area Bioengenharia
Mode of delivery Face to face
Work placements Not applicable.
Learning outcomes Prepare student for the first contact with Clinical Laboratory (CL)
Give students theoretical/practical training in the areas of Clinical Analysis
Provide clinical and laboratory knowledge for integration in specific teams
Consolidate the basic training to form an extension to areas of expertise Know the hierarchy of a CL
Apply knowledge of all valences in the understanding of the disease (and the action of drugs)
Learn to perform laboratory techniques with increasing complexity
Acquire practical skills including microscopy
Interpret the results of the External Quality Assessment (EQA)
Know how to apply statistical knowledge to evaluate the quality
Know how to work and apply the SPSS software
Identify and recognize changes in analytical parameters.
Interpret an analytical request and know how to fit the laboratory findings in different pathologies and underlying mechanisms
Identify laboratory cases of urgency
Know to use scientific reasoning in the search for self-learning
Syllabus UP1-1 LAC: Evolution/Quality
UP2-1Hematology
1.1Hematopoiesis
1.2Erythrocyte, leukocyte, platelet: associated diseases
1.3Hemostasis: evaluation
2Clinical Chemistry: Microbiology, Immunology, Endocrinology:
2.1Diabetes: changes in Renal/Lipidic functions in a patient
2.2Diabetes and CVD markers
2.4Renal funtion
2.5Urinary tract infection
2.6Renin-angiotensin-aldosterone system
2.7Other regulatory hormones
2.8Hepatitis: Etiology/diagnosis. Importance of hepatitis, cytomegalovirus, rubella, toxoplasmosis in pregnant women
3Tumor markers
UP3-SPSS: Theoretical-pratical application
TP/PL
Interpretation of analytical request
Blood count and platelets: automatic/manual counting
Cytograms/histograms
Description of Wintrobe and Westergreen techniques
Execution of blood smears
Differential leukocyte and reticulocyte count
Quantification of HbA1c and thyroid hormones
Urinalysis and bacteriological exam
Interpretation of different outcomes and resolution of practical cases
Main Bibliography Basic Bibliography
McPherson RA; Pincus MR. Henry’s Clinical Diagnosis and Management by Laboratory Methods, 22th Edition. Saunders, Elsevier (2012).
HillmanRS; Ault KA; Rinder H. Hematology in Clinical Practice, 5th Edition. McGraw-Hill, USA, (2011)
Guyton AC; Hall JE. Tratado de Fisiologia Médica, 12ªEdição. Editora: Elsevier (2011)
Supplementary Bibliography
Bishop, LM; Fody, PE; Schoeff L. Clinical Chemistry: Principles, Procedures, Correlations, 6th Edition. Lippincott Williams and Wilkins, Baltimore (2010)
Hoffbrand AV; Moss PAH; Pettit JE. Fundamentos em Hematologia, 6ªEdição. Artmed (2012)
Guyton AC; Hall JE. Fisiologia Humana e Mecanismos das Doenças, 6ªEdição. Guanabara Koogan, SA (2000)
Levey S; Jennings ER. The use of Control Charts in the Clinical Laboratory. Am J of Clin Path: 1059-1066 (1950)
http://fisiologia.med.up.pt/textos_apoio/sangue/hemograma.pdf
http://uscm.med.sc.edu:medicalmicrobiology.baron
http://brie.medlabscience.med.ualberta.ca/de/immunology
Language Portuguese. Tutorial support is available in English.
Last updated on: 2017-01-19

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