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Physics of Medical Imaging and Therapy

Code 13510
Year 1
Semester S1
ECTS Credits 6
Workload TP(60H)
Scientific area Biomedical Sciences
Entry requirements None.
Mode of delivery Face-to-face
Work placements Not applicable
Learning outcomes Explain the fundamental physical principles, concepts, methods and technologies used for different types of medical imaging and in radiotherapy. Evaluate the impact of current scientific and technological developments in the areas of medical imaging and radiotherapy. Discuss the importance of radiation safety in medical imaging with X-rays and radioisotopes, image quality versus dose to the patient, and in radiotherapy. Discuss topics in groups in the field of medical imaging and radiotherapy. Collect, organize information, write scientific papers and communicate orally to audiences consisting of specialists and non-experts in the field of physics of medical imaging and radiotherapy.
Syllabus 1. Interaction of radiation with matter:
1.1. X-rays and gamma rays interactions;
1.2. Interaction of charged particles;
1.3. Exposure and radiation dose.

2. Imaging with x-rays:
2.1. Conventional radiography, mammography, fluoroscopy and digital radiography;
2.2. Computed tomography (CT).

3. Ultrasound Imaging:
3.1. Physical principles;
3.2. Transducers;
3.3. Display modes;
3.4. Doppler imaging.

4. Magnetic resonance imaging:
4.1. Physical principles of nuclear magnetic resonance (NMR);
4.2. Pulse sequence;
4.3. Relaxation processes and measure;
4.4. Image acquisition in NMR.

5. Physical principles of nuclear medicine:
5.1. Radioactive decay;
5.2. Production of radionuclides;
5.3. Radiopharmaceuticals.

6. Radionuclide imaging (nuclear medicine):
6.1. Image Quality;
6.2. Conventional nuclear medicine (scintigraphy and SPECT);
6.3. Positron Emission Tomography (PET).

7. Use of radiation in therapy. Radionuclide therapy.
Main Bibliography 1. Main Bibliography:
“The Essential Physics of Medical Imaging”, Jerrold T. Bushberg, J. Anthony Seibert, Edwin M. Leidholdt Jr., John M. Boone, 2nd edition, 2001, Lippincott Williams & Wilkins.
“Physics in Nuclear Medicine”, Simon R. Cherry, James Sorenson, Michael Phelps, 3rd edition, 2003, Saunders.
“The Physics of Radiation Therapy”, Faiz M. Khan, 3rd edition, 2003, Lippincott Williams & Wilkins.

2. Complementary Bibliography:
“The Physics of Medical Imaging”, S. Webb, 1st edition, 1988, Taylor & Francis.
“Introductory Nuclear Physics”, K. S. Krane, 1988, New York: John Wiley.
“Radiation Detection and Measurement”, G. F. Knoll, 1989, New York: John Wiley.
Several review articles.
Teaching Methodologies and Assessment Criteria Theoretical-Practical lessons (TP): Oral lectures using audio-visual means, and the discussing of the concepts needed to understand the contents of the course. In order to consolidate the contents presented there will be problem solving tasks, individually or in groups, with further discussion of the resolution and results. Analysis and discussion of scientific papers selected for review by the teacher. It will be proposed the elaboration and oral presentation of a written essay, following a format of a scientific article, on a topic in physics of the image or medical therapy. Written Assessment (80%): three written tests during the teaching-learning period (with equal weight) or Exam. Continuous assessment (20%): preparation and oral presentation of a written essay (10%) and analysis and discussion of a scientific review article (10%). The approval of the course requires a minimum grade of 10 values (on a scale of 0-20) in all items of the assessment.
Language Portuguese. Tutorial support is available in English.
Last updated on: 2020-01-14

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