| Code |
13512
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| Year |
1
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| Semester |
S1
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| ECTS Credits |
6
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| Workload |
TP(60H)
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| Scientific area |
Biomedical Sciences
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Entry requirements |
N/A
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Mode of delivery |
Face-to-face
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Work placements |
Not applicable.
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Learning outcomes |
In addition to consolidating basic concepts of the organization and function of the immune system, and how an immune response is structured, the Clinical Immunology course will emphasize the fact that there may be functional failures in this system. These failures lead to inappropriate or dysfunctional immune responses that can result in a series of functional disorders in our body.
At the end of the Immunology Course, students should be able to:
1. Integrate and apply knowledge of Basic Immunology in the field of Clinical Immunology.
2. Apply the principles of clinical and laboratory diagnosis of diseases mediated by the immune system.
3. Analyze the basic principles of therapeutic intervention in the area of Clinical Immunology.
4. Perform critical analyses of research studies in Clinical Immunology.
5. Recognize the progress and limitations of Clinical Immunology.
6. Develop research projects in Clinical Immunology.
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Syllabus |
1. BASIC CONCEPTS IN IMMUNOLOGY (I) AND (II): Cells and Organs; Innate and Adaptive Immunity, Inflammatory Response; Adaptive Response
2. ALLERGIES: Generalities of Allergic Diseases. Clinical Cases. Diagnostic Techniques
3. HYPERSENSITIVITIES: Types. Immunopathology. Clinical Cases, Immunotherapy, and Corticosteroid Therapy.
4. IMMUNODEFICIENCIES: Primary and secondary immunodeficiencies.
5. Infectious Diseases and Vaccines: Viral Infections; Bacterial Infections; Parasitic Infections; Vaccination.
6. TOLERANCE AND AUTOIMMUNITY: Central and Peripheral Tolerance. Mechanisms for Maintaining and Breaking Tolerance.
7. AUTOIMMUNE DISEASES: Types. Immunopathological Aspects. Diagnostic Techniques.
8. TRANSPLANTATION: Alloreactivity and the MHC; Acute and Chronic Rejection; Immunosuppressive Therapies.
9. ONCOBIOLOGY: General Concepts; Characteristics of Tumors; Tumor Antigens.
10. TUMOR IMMUNOLOGY: Innate and Adaptive Responses. Escape Mechanisms of Tumors. Anti-Tumor Immunotherapies.
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Main Bibliography |
RECOMMENDED BIBLIOGRAPHY
1. Kuby Immunology, 8th Edition (2019). W.H. Freeman.
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Teaching Methodologies and Assessment Criteria |
853 / 5 000
Classical lectures, flipped classroom lectures and interactive seminars. Preparation of research project proposals written by students.
ASSESSMENT
1) Theoretical Assessment (AT, 16 points, 80%). Includes:
2) Theoretical-Practical Assessment (ATP, 4 points, 20%).
FINAL GRADE = AT x 0.8 + ATP x 0.2
WORKING STUDENTS
FINAL GRADE = AT (average of 2 tests)
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Language |
Portuguese. Tutorial support is available in English.
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