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Neurobiology

Code 13533
Year 1
Semester S2
ECTS Credits 6
Workload TP(60H)
Scientific area Biomedical Sciences
Entry requirements None
Mode of delivery Face-to-face
Work placements Not applicable
Learning outcomes At the end of the course the student should have

- acquired knowledge on:
The function of the constituent cells of the nervous system and on the mechanisms of neuronal communication.
Experimental methods used in neuroscience.
Provide basic concepts on neuroanatomy and the plasticity of the nervous system.

Concepts:
To know the cellular constitution of the nervous tissue and the forms of communication between the cells that constitute the nervous system.
Integrate knowledge about the basic mechanisms of functioning of the nervous system.
Relate the changes associated with some pathologies of the nervous system with the basic neuronal mechanisms.

Skills:
Understand the fundamentals of different laboratory techniques and be able to develop an experimental protocol.
Know how to analyze a scientific article.
Know how to synthesize information and transmit it clearly and accurately to colleagues.
Syllabus THE BRAIN AS A CELLULAR ECOSYSTEM

Nervous tissue as an integrated system

Glia as an active regulator of neural function

Biological rhythms and brain clearance

ENERGY, EXCITABILITY, AND COMMUNICATION
4. Neuronal and glial metabolism
5. Synaptic transmission
6. Synaptic plasticity and memory storage

NEUROTRANSMISSION SYSTEMS AND NETWORK FUNCTION
7. Fundamentals of neurotransmission
8. Excitatory and inhibitory systems
9. Diffuse modulatory systems

DYSFUNCTION, INFLAMMATION, AND DISEASE
10. Neuroinflammation and network dysregulation
11. Synaptic dysfunction and cellular vulnerability

Practical activities: Development of experimental protocols with models used in neuroscience.
Main Bibliography Neuroscience. Dale Purves, George J. Augustine, David Fitzpatrick , William C. Hall, Anthony-Samuel Lamantia, James O. McNamara , S. Mark Williams. Sinauer Associates.

Neurobiology: Molecules, Cells and Systems. Gary G. Matthews. Blackwell Publishers.

Basic Neurochemistry : Molecular, Cellular and Medical Aspects. George J. Siegel, R. Wayne Albers, Scott Brady, Donald L. Price. Academic Press.
Teaching Methodologies and Assessment Criteria Assessment by Continuous Evaluation

Assessment Components
A – Test 1: 8 points
B – Test 2: 8 points
C – Participation and interest in theoretical classes: 2 points
D – Report and presentation of the practical activity (group work): 2 points


Exam Assessment
A – Exam: 16 points
Components C and D, which cannot be repeated in the exam, retain their score.

Students with Worker-Student Status
Continuous Assessment

Assessment Components
A – Test 1: 9 points
B – Test 2: 9 points
C – Report and presentation of the practical activity (group work): 2 points

Exam Assessment
A – Exam: 18 points
To pass the exam, a grade higher than 10.0 (on a 0–20 scale) is required.
Component C, which cannot be repeated in the exam, retains its score.
Language Portuguese. Tutorial support is available in English.
Last updated on: 2026-03-03

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