Bioprocesses

Code	15859
Year	2
Semester	S2
ECTS Credits	6
Workload	TP(60H)
Scientific area	Biotecnologia
Entry requirements	-
Mode of delivery	Face-to-face with recourse to e-learning.
Work placements	Not applicable
Learning outcomes	Establish mass and energy balances in processes with and without chemical reaction. Solve combined mass and energy balances in transient regime. Know momentum, heat and mass transport phenomena. Perform calculations of heat and mass transfer in bioprocesses. At the end of this curricular unit, the student should be able to: - Design and interpret a flow diagram of an industrial chemical process; - Perform mass balances in systems with chemical reaction; - Perform energy balances in processes with phase transition and chemical reaction; - Carry out combined mass and energy balances with phase transition and chemical reaction, in steady state or batch systems.
Syllabus	Introduction to mass balances. Systems and processes. Flowsheet. Equilibrium and steady state. Mass balances with recycling, purge and bypass. Stoichiometry of growth and product formation. Balance to the atoms. Balance to the electrons. Yield. Energy balances. Enthalpy changes in processes with and without chemical reaction. Heat of reaction in processes with biomass production. Energy balances in microbial cultures.
Main Bibliography	• Lopes, A. M. C.; Nunes, M. J. "Apontamentos para a cadeira de Bioprocessos", UBI, Covilhã, 2002. • Hougen, O. A.; Watson, K. M.; Ragatz, R. A. "Princípios dos Processos Químicos", Ed. Lopes da Silva, 1972. • Himmelblau, D. M. "Basic Principles and Calculations in Chemical Engineering", 6th Ed., Prentice-Hall, New Jersey, 1996. • Lemos, F.; Madeira Lopes, J.; Ramôa Ribeiro, F. "Reactores Químicos", IST Press, 2002. • Nunes dos Santos, A.M. "Reactores Químicos", vol. I, Fundação Calouste Gulbenkian ed., 1990. • Baley, J.E.; Ollis, D.F. "Biochemical Engineering Fundamentals ", 2nd Ed., McGraw-Hill, 1986. • Nielsen, J.; Villadsen, J.; Lidén, G. "Bioreaction Engineering Principles", 2nd Ed., Kluwer Academic/ Plenum Plublishers, New York, 2003. • "Perry’s Chemical Engineer’s Handbook", 7th Ed., Perry, R.H., Green, D.W.; Maloney, J.O. (Eds) McGraw-Hill, New York, 1999.
Teaching Methodologies and Assessment Criteria	Teaching-Learning Classification (TLC) Continuous assessment - consists of three written partial assessment tests (theoretical and theoretical-practical). • 1st test – 17th April • 2nd test – 20th May • 3rd test - 9th June The final classification (CF) will be assigned according to the following formula: CF = 0.50 x NT1 + 0.25 x NT2 + 0.25 x NT3 where NT1, NT2 and NT3 are the scores obtained in the 1st, 2nd and 3rd tests, respectively. PASS if: - Final classification (CF) equal to or greater than 9.5 values. FREQUENCY if: - 75% attendance in classes (Student-workers - does not apply to attendance condition) Final Classification by Exam Exam grade equal to or greater than 9.5 values. Students may choose to take the entire exam or just parts of it, either to pass or to improve their grade.
Language	Portuguese. Tutorial support is available in English.