| Code |
8634
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| Year |
2
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| Semester |
S1
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| ECTS Credits |
6
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| Workload |
PL(30H)/T(30H)
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| Scientific area |
Chemistry
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Entry requirements |
Not applicable.
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Mode of delivery |
Face-to-face with recourse to e-learning
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Work placements |
Not applicable.
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Learning outcomes |
This course unit aims to teach the basic knowledge to classify the main types of reactions in organic chemistry and its understanding through its mechanism. At the end of the course unit the student should be able to combine the basic knowledge learned in the course unit with an adequate bibliographic support, in order to predict and classify the chemical behavior of compounds belonging to the main functional groups. It aims also to encourage literature research and reading habits, thus stimulating self-learning in order to solve the proposed problems and to develop a seminar about a theme related with both pharmaceutical sciences and organic chemistry
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Syllabus |
1 Reactions in Organic Chemistry
1.1 Main types
1.2 Reaction mechanisms and the use of curved arrows utilization to their illustration.
2 Saturated carbons
2.1 Nucleophilic substitution reactions
2.2 Elimination reactions
2.3 Radical reactions
3 Unsaturated carbons
3.1 Electrophilic addition
3.2 Conjugated systems
3.3 Alkenes formation
4 Carbonyl group
4.1 Nucleophilic addition
4.2 Conjugate addition
4.3 Substitution
5 Oxidation-reduction reactions
6 Enols and Enolates: reactions and formation
Practical classes:
- Indolin-2,3-dione reduction with NaBH4 and NH2NH2 (Wolff- Kishner reduction) – A practical example of microwaves in organic synthesis (2 classes)
- Arrows in Organic Chemistry. Introduction to reaction mechanisms
- Saturated Carbons
- Unsaturated Carbons
- Carbonyl Group
- Oxidation Reduction + Enols and enolates
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Main Bibliography |
- T. W. G. Solomons, C. B. Fryle, Química Orgânica, Vol. 1 e 2, 10ª ed., LTC Livros Técnicos e Científicos Editora S. A.: Rio de Janeiro, 2012.
2. Recommended reading:
- M. M. M. Pinto, Manual de Trabalhos Laboratoriais de Química Orgânica e Farmacêutica,Lidel – edições técnicas lda: Lisboa, 2011.
- M. B. Smith, J. March, March’s Advanced Organic Chemistry – Reactions, Mechanisms and Structure, 7th ed., John Wiley & Sons: New York, 2013.
- F.A. Carey, R.J. Sundberg, Advanced Organic Chemistry Part A: Structure and Mechanisms, 5th ed,Springer, New York, 2007.
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Teaching Methodologies and Assessment Criteria |
Oral presentation of matter with the help of the frame and slide, with great teacher-student interactivity,
promoting discussion between students and teacher to ensure the participation and interest in the subjects
taught. The classes are divided into laboratory classes, where students made the synthesis of organic
compounds, and lessons of resolution of problems related to the subjects taught. Students will develop a
seminar on a theme, relating the knowledge learned in organic synthesis or modification of compounds,
establishing a written work which, at the end of the semester, will be presented to colleagues. Learner
assessment is conducted on an ongoing basis are considered three evaluation factors:
10% P% S + 20 + 70% T where:
T = marks obtained in written tests during the teaching-learning or examination period;
S = grade obtained in the seminar;
P = performance evaluation laboratory
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Language |
Portuguese. Tutorial support is available in English.
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