| Code |
12834
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| Year |
3
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| Semester |
S2
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| ECTS Credits |
6
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| Workload |
PL(15H)/T(30H)/TP(15H)
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| Scientific area |
Biochemistry
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Entry requirements |
Not applicable
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Mode of delivery |
Face to Face with recourse to e-learning.
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Work placements |
Not applicable.
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Learning outcomes |
The learning objectives aim for students to acquire solid knowledge of biosensors, including their architecture, molecular recognition components, transducers, and analytical validation, as well as to understand their practical applications. The skills developed include critical analysis of measurement systems, selection of immobilization methods, interpretation of performance parameters, and evaluation of innovative solutions. Competencies encompass teamwork, scientific communication, and autonomy in problem-solving. The teaching method, combining theoretical lectures, case discussions, study of recent applications, and development of mini-projects, ensures alignment with these objectives, enabling students to integrate theory and practice, develop experimental and analytical skills, and apply knowledge to real and innovative contexts.
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Syllabus |
1. Overview of Biosensors:
1.1. Introduction to biosensor architecture.
1.2. Block diagram of the measurement system.
1.3. Ideal requirements.
1.4. Classification of biosensors.
2. Molecular Recognition Components:
2.1. Different types of molecular recognition components – General aspects, advantages, and disadvantages.
2.2. Methods for immobilizing molecular recognition components.
3. Transducers Used in Biosensors:
3.1. Electrochemical transducers. 3.2. Optical transducers.
3.3. Miniaturization of biosensors – application of nanomaterials.
3.4. Acoustic wave transducers.
3.5. Thermal transducers.
4. Performance Parameters and Evaluation of Biosensors:
4.1. Validation requirements for biosensors.
4.2. Analytical validation characteristics of biosensors.
5. Recent Applications of Biosensors:
5.1. Health (Point-of-care sensing).
5.2. Food safety and water monitoring.
5.3. Environmental pollutants.
6. Mini-projects.
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Main Bibliography |
• Biosensors: Fundamentals, Emerging Technologies, and Applications / edited by Edited by Sibel A. Ozkan, Bengi Uslu, and Mustafa Kemal Sezgintürk, CRC Press, Taylor & Francis Group, 2023.
• Biosensors : fundamentals and applications / edited by Bansi Dhar Malhotra and Chandra Mouli Pandey, Smithers Rapra Technology Ltd, 2017
• Chemical Sensors and Biosensors: fundamentals and Applications / edited by Florinel-Gabriel Banica, John Wiley & Sons, 2012.
• www.journals.elsevier.com/biosensors-and-bioelectronics/
• Miscellaneous articles.
• Teachers notes on the Moodle platform.
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Teaching Methodologies and Assessment Criteria |
The teaching-learning activities are based on theoretical, theoretical-practical and laboratory classes, in which the objectives to be achieved (learning objectives) will be identified by topic. In theoretical classes, means of active learning are introduced, resorting to the use of mobile phones, specifically questionnaires are introduced with distractors that reflect common misconceptions of students. To encourage their participation, competitions are also held during these questionnaires and the results displayed in a histogram in order to alert students to their mistakes. Videos are also shown (always complemented with questions) that illustrate the construction and functioning of the different types of biosensors to be addressed in the UC.
Theoretical-practical and laboratory classes are focused on project-based learning. 4 mini-projects are carried out. In these, students are organized into groups of 2/3 students and given the problem to be solved.
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Language |
Portuguese. Tutorial support is available in English.
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