| Code |
16888
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| Year |
1
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| Semester |
S2
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| ECTS Credits |
5
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| Workload |
TP(40H)
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| Scientific area |
BIOMEDICINA/BIOQUÍMICA/MEDICINA/CIÊNCIAS FARMACÊUTICAS
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Entry requirements |
No requirements.
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Learning outcomes |
The Curricular Unit allows students to acquire an overview of antimicrobial resistance and its spread, as well as to identify innovative approaches in this area. Thus, students should acquire the following knowledge/skills:
I) To describe the concepts associated with mechanisms of action and antibiotic resistance;
II) To describe and discuss parameters associated with the evolution of resistance;
III) To describe the genetic mechanisms for the spread of resistance;
IV) To discuss the “One Health” perspective in antimicrobial resistance, as an approach that recognizes the link between Human and animal health and the link with the shared environment;
V) To present skills in the assessment of antimicrobial susceptibility and resistance mechanisms, based on phenotypic and advanced molecular technologies;
VI) To understand the process associated with the development of new antimicrobial compounds
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Syllabus |
I) Basic concepts in antibiotics and antibiotic resistance
II) Evolution of resistance and genetic mechanisms for its spread
III) The “One Health” perspective on antimicrobial resistance
IV) Antimicrobial susceptibility tests and resistance mechanisms
V) Whole genome sequencing in the molecular epidemiology of antimicrobial resistance
VI) Alternative strategies to combat antimicrobial resistance
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Main Bibliography |
• José-Luis Capelo-Martínez, Gilberto Igrejas. (2019) Antibiotic Drug Resistance. John Wiley & Sons, Inc. Online ISBN:9781119282549, DOI:10.1002/9781119282549
• Sabu Thomas. (2020) Antimicrobial Resistance - Global Challenges and Future Interventions. Springer, Singapore. eBook ISBN 978-981-15-3658-8, doi: 10.1007/978-981-15-3658-8
• Scientific paper provided.
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Teaching Methodologies and Assessment Criteria |
The approval of the curricular unit will be obtained with a minimum final grade of ten values, on a scale from zero to twenty values (0-20). Failure to obtain approval through continuous assessment requires the student to take an exam covering all syllabus contents, during the designated exam periods.
The evaluation includes a test (70%) and preparation of a monograph considering the global application of an advanced molecular methodology for assessing the resistance of infectious agents among those classified as ESKAPEE (30%). This will allow to ascertain the degree of understanding of the information transmitted, thus as their framing and the critical thinking ability of the student.
If a grade lower than 6 (out of 20) is obtained in any assessment component (test or monograph), the student will be required to take the exam.
Students who fail the teaching-learning assessment may take the exam in the normal and resit period, provided they meet the minimum requirements.
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Language |
Portuguese. Tutorial support is available in English.
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