| Code |
16888
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| Year |
1
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| Semester |
S2
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| ECTS Credits |
5
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| Workload |
TP(40H)
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| Scientific area |
BIOMEDICINA/BIOQUÍMICA/MEDICINA/CIÊNCIAS FARMACÊUTICAS
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Entry requirements |
No requirements.
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Learning outcomes |
The Curricular Unit allows students to acquire an overview of antimicrobial resistance and its spread, as well as to identify innovative approaches in this area. Thus, students should acquire the following knowledge/skills:
I) To describe the concepts associated with mechanisms of action and antibiotic resistance;
II) To describe and discuss parameters associated with the evolution of resistance;
III) To describe the genetic mechanisms for the spread of resistance;
IV) To discuss the “One Health” perspective in antimicrobial resistance, as an approach that recognizes the link between Human and animal health and the link with the shared environment;
V) To present skills in the assessment of antimicrobial susceptibility and resistance mechanisms, based on phenotypic and advanced molecular technologies;
VI) To understand the process associated with the development of new antimicrobial compounds
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Syllabus |
I) Basic concepts in antibiotics and antibiotic resistance
II) Evolution of resistance and genetic mechanisms for its spread
III) The “One Health” perspective on antimicrobial resistance
IV) Antimicrobial susceptibility tests and resistance mechanisms
V) Whole genome sequencing in the molecular epidemiology of antimicrobial resistance
VI) Alternative strategies to combat antimicrobial resistance
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Main Bibliography |
• José-Luis Capelo-Martínez, Gilberto Igrejas. (2019) Antibiotic Drug Resistance. John Wiley & Sons, Inc. Online ISBN:9781119282549, DOI:10.1002/9781119282549
• Sabu Thomas. (2020) Antimicrobial Resistance - Global Challenges and Future Interventions. Springer, Singapore. eBook ISBN 978-981-15-3658-8, doi: 10.1007/978-981-15-3658-8
• Scientific paper provided.
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Teaching Methodologies and Assessment Criteria |
The approval of the curricular unit will be obtained with a minimum final grade of ten values, on a scale from zero to twenty values (0-20). Failure to pass implies taking an exam, at the times provided for that purpose, considering the full syllabus. The evaluation includes a test (70%) and preparation of a monograph considering the global application of an advanced methodology for assessing the resistance of infectious agents among those classified as ESKAPE (30%). This will allow to ascertain the degree of understanding of the information transmitted, thus as their framing and the critical thinking ability of the student.
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Language |
Portuguese. Tutorial support is available in English.
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