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Cecília Reis Alves dos Santos

Professor/a Associado/a com Agregação

Sector — Cargos/Funções

CICS - Centro de Investigação em Ciências da Saúde Responsável/CICS - Health Sciences Research Center

Departamento de Ciências Médicas Docente do Departamento de Ciências Médicas

Publicações Científicas Mais Recentes

(Informação importada da plataforma CiênciaVitae)

    Artigo em conferência/Conference paper

    1. Maia, Claúdio J. B.; Vaz, CV; Peres, Carina; SANTOS, Cecilia R A; Socorro, Sílvia. "Regucalcin, a calcium-binding protein, is a new target gene in human prostate cancer?". 2010.
    2. Santos, C.R.A.; Power, D.M.. "Piscine (Sparus aurata) transthyretin cDNA cloning and characterization". 1998.

    Artigo em revista/Journal article

    1. Ana R. Costa; Ana C. Duarte; Ana R. Costa-Brito; Isabel Gonçalves; Cecília R.A. Santos. "Bitter taste signaling in cancer". Life Sciences (2023) url
    2. André Furtado; André J. Esgalhado; Ana Catarina Duarte; Ana R. Costa; Ana R. Costa-Brito; Eva Carro; Hiroshi Ishikawa; et al. "Circadian rhythmicity of amyloid-beta-related molecules is disrupted in the choroid plexus of a female Alzheimer''''s disease mouse model". Journal of Neuroscience Research (2023) url
    3. André Furtado; Diana Costa; Lemos, Manuel C; J Eduardo Cavaco; SANTOS, Cecilia R A; Quintela, Telma. Autor correspondente: Quintela, Telma. "The impact of biological clock and sex hormones on the risk of disease.". Advances in Protein Chemistry and Structural Biology (2023) url
    4. Rafael Mineiro; Cecília Santos; Isabel Gonçalves; Manuel Lemos; José Eduardo B. Cavaco; Telma Quintela. "Regulation of ABC transporters by sex steroids may explain differences in drug resistance between sexes". Journal of Physiology and Biochemistry (2023) url
    5. Rafael Mineiro; Tânia Albuquerque; Ana Raquel Neves; Cecília R. A. Santos; Diana Costa; Telma Quintela. "The Role of Biological Rhythms in New Drug Formulations to Croay the Brain Barriers". International Journal of Molecular Sciences (2023) url

    Capítulo de livro/Book chapter

    1. Furtado, André; Costa, Diana; Lemos, Manuel C.; Cavaco, J. Eduardo; Santos, Cecília R.A.; Quintela, Telma. "The impact of biological clock and sex hormones on the risk of disease". In Advances in Protein Chemistry and Structural Biology, 39-81: Elsevier, 2023.
    2. Gonçalves, Isabel; Quintela, Telma; Duarte, Ana Catarina; Hubbard, Peter; Baltazar, Graça; Schwerk, Christian; Belin, Andrea Carmine; Tomás, Joana; Santos, Cecília Reis A. "Experimental Tools to Study the Regulation and Function of the Choroid Plexus". In Blood-Brain Barrier, 205-230: Springer New York, 2019.
    3. Santos, Cecilia. "Estrogens and prostate cancer: from biosynthesis to physiological effects Gomes IM, Vaz C, Rodrigues D, Rocha SM, Socorro S, Santos CR, Maia CJ 01/2013; ISBN: ISB_Estrogens and prostate cancer_ from biosynthesis to physiological effeN: 978-1-62808-96". In Estradiol: synthesis, Health Effects and Drug Interactions, 2013.
    4. A Santos, Cecilia R; Cardoso, Isabel; Goncalves, Isabel. "Key Enzymes and Proteins in Amyloid-Beta Production and Clearance". In Alzheimer''''s Disease Pathogenesis-Core Concepts, Shifting Paradigms and Therapeutic Targets: InTech, 2011.

    Nota Biográfica

    (Informação importada da plataforma CiênciaVitae)
    I graduated in Marine Biology and Fisheries from the University of Algarve in 1992, where I subsequently pursued my PhD in molecular biology from 1994 to 1999, followed by a Post-Doc in fish molecular endocrinology from 2000 to 2002. In 2002, I embarked on a new chapter of my career as an assistant professor at the University of Beira Interior (FCS-UBI), later earning promotion to associate professor in 2011 through international competition. Furthering my academic achievements, I attained the aggregation title in Biomedicine at UBI in 2019. My transition to UBI marked a pivotal moment in my professional journey, entailing active involvement in establishing research laboratories and outfitting temporary facilities, culminating in the design and equipping of the current facilities at the CICS-UBI building, which we relocated to in 2007/2008. During this period, I forged my research niche in biomedical sciences, initially exploring cancer research before redirecting my focus to the choroid plexus (CP), a critical brain barrier, where I have since made significant scientific contributions. Additionally, I have a keen interest in investigating the impact of sex hormone backgrounds on biological processes and the onset of neuronal diseases and cancer, highlighting the importance of tailored therapeutic approaches based on individuals'' biological sex. My involvement in research extends beyond project leadership; I have served as principal investigator (PI) on three FCT-funded projects totaling €340,000, as well as participating as a team member in several other projects. Furthermore, I have supervised numerous PhD and Master''s students, guiding them to successful thesis completion. Complementing my research endeavors, I have been actively engaged in teaching molecular and cellular biology, anatomy, histology, and physiology to medical and biomedical students, along with oncobiology to Master''s students of Biochemistry and Biomedical Sciences. In addition to my academic roles, I have plssed a significant role in faculty and research center decision-making bodies, including coordinating various research groups and assuming leadership positions within the CICS-UBI research center. Most recently, I have taken on the role of vice-coordinator at CICS-UBI, continuing to contribute to its academic and research excellence.

    Distinções e Prémios

    (Informação importada da plataforma CiênciaVitae)
    2019Agregação - Universidade da Beira Interior Centro de Matemática e Aplicações, Covilhã, Castelo Branco, Portugal

    Projectos e Financiamentos

    (Informação importada da plataforma CiênciaVitae)


    Clock ABC FBR_OC2_78  (Em curso)
    "Gliorganoides" - Development of GB organoids, originated from GB cell lines, for preclinical evaluation of the anti-proliferative effect of lactisole " CENTRO-01-0246-FEDER-000044 (Concluído)
    Investigation on the role of the glucosensing receptor T1R3 in glioblastoma hallmarks (STARvE) NA (Em curso)
    Relationship between adenosine and chromosomal instability: a new perspective to understand the oncogenic mechanism in glioblastoma PTDC/BIM-ONC/ 7121/2014 (Concluído)


    Suportes modificados com Liquidos Iónicos para a Purificação de pré-miRNAs envolvidos na doença de Alzheimer PTDC/BII-BBF/29496/2017 (Em curso)



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